Table 4 Bipolar 1 vs. 2 subjects: treatment
From: Differences between bipolar disorder types 1 and 2 support the DSM two-syndrome concept
Measure | Mean or percentage [95%CI] | RR | p-value | |
|---|---|---|---|---|
BD-1 | BD-2 | (BD-1/BD-2) | [t or χ2] | |
Subjects (n) | 657 | 720 | 1/1.10 | – |
Lithium use | ||||
Treated (%) | 65.0 [61.2–68.6] | 49.6 [45.9–53.3] | 1.27 | < 0.0001 [33.3] |
Dose (mg/day) | 828 [796–860] | 609 [577–641] | 1.36 | < 0.0001 [9.46] |
Mean level (mEq/L) | 0.61 [0.58–0.65] | 0.56 [0.51–0.61] | 1.09 | 0.11 [1.62] |
Lithium + other drugs (%) | 20.6 [16.4–25.3] | 18.0 [13.2–23.6] | 1.14 | 0.44 [0.59] |
Other treatments (%) | ||||
Antidepressants | 41.7 [37.3–46.2] | 71.0 [67.0–74.8] | 1/1.70 | < 0.0001 [90.2] |
Anticonvulsants | 39.1 [35.4–42.9] | 34.3 [30.9–37.8] | 1.14 | 0.06 [3.62] |
Antipsychotics | 19.9 [16.9–23.0] | 8.20 [6.33–10.4] | 2.43 | < 0.0001 [40.8] |
Benzodiazepines | 8.76 [6.75–11.1] | 15.7 [13.2–18.5] | 1/1.79 | < 0.0001 [16.0] |
Psychotherapy | 40.1 [34.4–50.8] | 45.4 [40.4–50.8] | 1/1.13 | 0.17 [1.88] |