Table 5 Highly significant differences between BD-2 and BD-1 subjects
From: Differences between bipolar disorder types 1 and 2 support the DSM two-syndrome concept
More with BD-2 | More with BD-1 |
|---|---|
Familial mood disorders | Obesity |
Older at: first symptoms, syndrome, diagnosis, treatment | Drug and alcohol abuse; cigarettes/day |
Educated > high school | First episode [hypo]manic |
Employed | First episode psychotic |
Ever married | Higher intake scores: YMRS, MDQ |
Children | Spring–summer seasonal [hypo]mania |
Higher SES rating | %-Time [hypo]manic |
Cyclothymic temperament | Psychiatric hospitalizations/year |
Co-occurring general medical and anxiety disorders | Violent suicidal acts |
First lifetime episode: depressive and longer | Use of lithium and mg/day doses |
Intake depression (HDRS, MADRS) and anxiety (HARS) | HDRS items: psychomotor retardation, paranoia |
HDRS items: depressed mood, guilt, suicidal, insomnia, agitation, psychic and somatic anxiety, hypochondriasis, weight-loss, circadian mood-fluctuation, total score | |
%-Time depressed | |
Predominant depression | |
DMI course pattern | |
Rapid or continuous cycling | |
Prescribed antidepressants and benzodiazepines |