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  1. Even though United Nation announced that all persons with a mental illness shall be treated with humanity and respect for the inherent dignity of the human being, up to now, the use of coercion (physical restr...

    Authors: Habte Belete

    Citation: International Journal of Bipolar Disorders 2017 5:17

    Content type: Research

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  2. Bipolar disorder is a chronic illness with a 2-year recurrence rate of approximately 50% among individuals receiving treatment in the community. The aim of this 18-month, open-label, continuation study was to ...

    Authors: Andrei Pikalov, Joyce Tsai, Yongcai Mao, Robert Silva, Josephine Cucchiaro and Antony Loebel

    Citation: International Journal of Bipolar Disorders 2017 5:9

    Content type: Research

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  3. Until recently, actigraphy studies in bipolar disorders focused on sleep rather than daytime activity in mania or depression, and have failed to analyse mixed episodes separately. Furthermore, even those studi...

    Authors: Jan Scott, Arne E. Vaaler, Ole Bernt Fasmer, Gunnar Morken and Karoline Krane-Gartiser

    Citation: International Journal of Bipolar Disorders 2017 5:5

    Content type: Research

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  4. Despite the use of maintenance medication, recurrence rates in bipolar affective disorder (BPAD) are high. To date, there are no clinical trials that have investigated the use of psychological interventions i...

    Authors: Muhammad Ishrat Husain, Imran B. Chaudhry, Raza R. Rahman, Munir M. Hamirani, Nasir Mehmood, Peter M. Haddad, John Hodsoll, Allan H. Young, Farooq Naeem and Nusrat Husain

    Citation: International Journal of Bipolar Disorders 2017 5:3

    Content type: Research

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  5. The digital revolution in medicine not only offers exciting new directions for the treatment of mental illness, but also presents challenges to patient privacy and security. Changes in medicine are part of the...

    Authors: Michael Bauer, Tasha Glenn, Scott Monteith, Rita Bauer, Peter C. Whybrow and John Geddes

    Citation: International Journal of Bipolar Disorders 2017 5:6

    Content type: Review

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  6. In the last two decades, there has been a significant increase in the diagnosis of Bipolar Disorder (BD) in children. The notion of prepubertal onsets of BD is not without controversy, with researchers debatin...

    Authors: Faye Ryles, Thomas D. Meyer, Jaime Adan-Manes, Iain MacMillan and Jan Scott

    Citation: International Journal of Bipolar Disorders 2017 5:4

    Content type: Review

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  7. Bipolar disorder (BD) is a chronic, frequently comorbid condition characterized by high rates of mood episode recurrence and suicidality. Little is known about prospective longitudinal characterization of BD ...

    Authors: Bernardo Dell’Osso, Saloni Shah, Dennis Do, Laura D. Yuen, Farnaz Hooshmand, Po W. Wang, Shefali Miller and Terence A. Ketter

    Citation: International Journal of Bipolar Disorders 2017 5:2

    Content type: Research

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  8. Previous studies of our group among bipolar offspring and bipolar twins showed significant higher prevalence’s and levels of antithyroid peroxidase antibodies (TPO-Abs) in offspring and co-twins (without a moo...

    Authors: G. Snijders, L. de Witte, E. Mesman, S. Kemner, R. Vonk, R. Brouwer, W. A. Nolen, H. A. Drexhage and M. H. J. Hillegers

    Citation: International Journal of Bipolar Disorders 2017 5:1

    Content type: Short communication

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  9. Mood stabilizers like lithium and anticonvulsants are used in bipolar and related psychotic disorders. There is a lack of knowledge of the relationship of these medications and cognition in the psychosis spect...

    Authors: Nils Eiel Steen, Monica Aas, Carmen Simonsen, Ingrid Dieset, Martin Tesli, Mari Nerhus, Erlend Gardsjord, Ragni Mørch, Ingrid Agartz, Ingrid Melle, Anja Vaskinn, Olav Spigset and Ole A. Andreassen

    Citation: International Journal of Bipolar Disorders 2016 4:24

    Content type: Research

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  10. Bipolar disorder is a severe and heterogeneous mental disorder. Despite great advances in neuroscience over the past decades, the precise causative mechanisms at the transmitter, cellular or network level have...

    Authors: Philipp S. Ritter, Felix Bermpohl, Oliver Gruber, Martin Hautzinger, Andreas Jansen, Georg Juckel, Tilo Kircher, Martin Lambert, Christoph Mulert, Andrea Pfennig, Andreas Reif, Otto Rienhoff, Thomas G. Schulze, Emanuel Severus, Thomas Stamm and Michael Bauer

    Citation: International Journal of Bipolar Disorders 2016 4:26

    Content type: Review

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  11. “Nothing is more difficult than to ascertain the length of time that a maniacal patient can exist without sleep.”—Dr. Sutherland (Br J Psychiatry 7(37):1–19, 1861). Dr. Sutherland’s patient was suffering from an ...

    Authors: John Torous, Paul Summergrad and S. Nassir Ghaemi

    Citation: International Journal of Bipolar Disorders 2016 4:25

    Content type: Short communication

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  12. Despite growing consensus on nosology and epidemiology of bipolar disorder (BD) in minors, differences remain. We contribute to this discussion by measuring long-term trends in the inpatient discharge rates of...

    Authors: Pradeep Rao, Julie K. Moore, Richard Stewart, Kevin Runions, Natasha Bear, Janice W. Y. Wong, Martin Holtmann and Florian D. Zepf

    Citation: International Journal of Bipolar Disorders 2016 4:23

    Content type: Reseach

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  13. Bipolar disorder is a chronic illness that impairs functioning and affects the quality of life of patients. The onset of this illness usually occurs at an early age, and the risk of relapse remains high for de...

    Authors: Susana Alberich, Sara Barbeito, Itxaso González-Ortega, Amaia Ugarte, Patricia Vega, Sonia Ruiz de Azúa, Purificación López, Iñaki Zorrilla and Ana González-Pinto

    Citation: International Journal of Bipolar Disorders 2016 4:22

    Content type: Research

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  14. Anabaptists comprise large and growing Amish and Mennonite populations with a unique genetic heritage and cultural background. Little is known about the symptoms and course of major mood disorders in Anabaptis...

    Authors: Kelly E. Gill, Stephanie A. Cardenas, Layla Kassem, Thomas G. Schulze and Francis J. McMahon

    Citation: International Journal of Bipolar Disorders 2016 4:21

    Content type: Research

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  15. Research on theory of mind (ToM) abilities in patients with bipolar disorder has yielded conflicting results. Meta-analyses point to a stable moderate impairment in remitted patients, but factors such as subsy...

    Authors: Silvia Haag, Paula Haffner, Esther Quinlivan, Martin Brüne and Thomas Stamm

    Citation: International Journal of Bipolar Disorders 2016 4:20

    Content type: Research

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  16. This case chronicles the unique presentation of psychotic mixed mania in a female 5 months after parturition and 1 week following breastfeeding discontinuation, highlighting a rarely recognized mania risk fact...

    Authors: Kristen A. Schmidt, Brian A. Palmer and Mark A. Frye

    Citation: International Journal of Bipolar Disorders 2016 4:18

    Content type: Case report

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  17. Information seeking is an important coping mechanism for dealing with chronic illness. Despite a growing number of mental health websites, there is little understanding of how patients with bipolar disorder us...

    Authors: Jörn Conell, Rita Bauer, Tasha Glenn, Martin Alda, Raffaella Ardau, Bernhard T. Baune, Michael Berk, Yuly Bersudsky, Amy Bilderbeck, Alberto Bocchetta, Letizia Bossini, Angela Marianne Paredes Castro, Eric Yat Wo Cheung, Caterina Chillotti, Sabine Choppin, Maria Del Zompo…

    Citation: International Journal of Bipolar Disorders 2016 4:17

    Content type: Research

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    The Erratum to this article has been published in International Journal of Bipolar Disorders 2017 5:18

  18. Impulsivity as a tendency to act quickly without considering future consequences has been proposed as a dimensional factor in bipolar disorder. It can be measured using behavioral tasks and self-report questio...

    Authors: Elisa Sophie Strasser, Paula Haffner, Jana Fiebig, Esther Quinlivan, Mazda Adli and Thomas Josef Stamm

    Citation: International Journal of Bipolar Disorders 2016 4:16

    Content type: Research

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  19. Current irritability is associated with greater retrospective and current bipolar disorder (BD) illness severity; less is known about prospective longitudinal implications of current irritability. We examined ...

    Authors: Laura D. Yuen, Saloni Shah, Dennis Do, Shefali Miller, Po W. Wang, Farnaz Hooshmand and Terence A. Ketter

    Citation: International Journal of Bipolar Disorders 2016 4:15

    Content type: Research

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  20. The association between inflammation and the course of mood disorders is receiving increased attention. This study aims to investigate whether a sub-group of patients with BD can be identified for which a high...

    Authors: Sonya M. Balukova, Bartholomeus C. M. Haarman, Rixt F. Riemersma-van der Lek and Robert A. Schoevers

    Citation: International Journal of Bipolar Disorders 2016 4:14

    Content type: Research

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  21. Bipolar disorder refers to a group of chronic psychiatric disorders of mood and energy levels. While dramatic psychiatric symptoms dominate the acute phase of the diseases, the chronic course is often determin...

    Authors: Ellen F. Charles, Christophe G. Lambert and Berit Kerner

    Citation: International Journal of Bipolar Disorders 2016 4:13

    Content type: Review

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  22. Differences in cortisol secretion may differentiate individuals at high compared to low genetic risk for bipolar disorder (BD) and predict the onset or recurrence of mood episodes. The objectives of this study...

    Authors: Sarah M. Goodday, Julie Horrocks, Charles Keown-Stoneman, Paul Grof and Anne Duffy

    Citation: International Journal of Bipolar Disorders 2016 4:12

    Content type: Research

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  23. Genetic vulnerability to environmental stressors is yet to be clarified in bipolar disorder (BD), a complex multisystem disorder in which immune dysfunction and infectious insults seem to play a major role in ...

    Authors: José Oliveira, Rémi Kazma, Edith Le Floch, Meriem Bennabi, Nora Hamdani, Djaouida Bengoufa, Mehdi Dahoun, Céline Manier, Frank Bellivier, Rajagopal Krishnamoorthy, Jean-François Deleuze, Robert Yolken, Marion Leboyer and Ryad Tamouza

    Citation: International Journal of Bipolar Disorders 2016 4:11

    Content type: Research

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  24. The delivery of psychiatric care is changing with a new emphasis on integrated care, preventative measures, population health, and the biological basis of disease. Fundamental to this transformation are big da...

    Authors: Scott Monteith, Tasha Glenn, John Geddes, Peter C. Whybrow and Michael Bauer

    Citation: International Journal of Bipolar Disorders 2016 4:10

    Content type: Review

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  25. Evidence suggests that patients with bipolar disorder (BD) experience biological rhythm disturbances; however, no studies have examined the impact of this disruption on quality of life (QOL). The aim of this s...

    Authors: Lauren E. Cudney, Benicio N. Frey, David L. Streiner, Luciano Minuzzi and Roberto B. Sassi

    Citation: International Journal of Bipolar Disorders 2016 4:9

    Content type: Research

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  26. Bipolar depression is characterized by depressive symptoms and impairment in many areas of functioning, including work, family, and social life. The objective of this study was to assess the independent, direc...

    Authors: Krithika Rajagopalan, Elizabeth Dansie Bacci, Kathleen W. Wyrwich, Andrei Pikalov and Antony Loebel

    Citation: International Journal of Bipolar Disorders 2016 4:7

    Content type: Research

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  27. Ecological momentary sampling in BD research requires brief symptom measures with low cognitive demands to maximize data collection across the range of BD symptomatology. We developed the BD Sx cognizant of the c...

    Authors: Norm O’Rourke, Andrew Sixsmith, David B. King, Hamed Yaghoubi-Shahir and Sarah L. Canham

    Citation: International Journal of Bipolar Disorders 2016 4:8

    Content type: Research

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  28. Behavioral and emotional adverse events induced by drugs commonly prescribed to patients with bipolar disorders are of paramount importance to clinical practice and research. However, no reviews on the topic h...

    Authors: Alejandro Szmulewicz, Cecilia Samamé, Pablo Caravotta, Diego J. Martino, Ana Igoa, Diego Hidalgo-Mazzei, Francesc Colom and Sergio A. Strejilevich

    Citation: International Journal of Bipolar Disorders 2016 4:6

    Content type: Review

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  29. Mood disorders and circulating thyroid antibodies are very prevalent in the population and their concomitant occurrence may be due to chance. However, thyroid antibodies have been repeatedly hypothesized to p...

    Authors: Alberto Bocchetta, Francesco Traccis, Enrica Mosca, Alessandra Serra, Giorgio Tamburini and Andrea Loviselli

    Citation: International Journal of Bipolar Disorders 2016 4:5

    Content type: Review

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  30. Despite the rapid growth in the sophistication of research on bipolar disorder (BD), the field faces challenges in improving quality of life (QoL) and symptom outcomes, adapting treatments for marginalized com...

    Authors: Erin E. Michalak, Steven Jones, Fiona Lobban, Guillermo Perez Algorta, Steven J. Barnes, Lesley Berk, Michael Berk, Rachelle Hole, Sara Lapsley, Victoria Maxwell, Roumen Milev, John McManamy, Greg Murray, Mauricio Tohen, Samson Tse, Manuel Sanchez de Carmona…

    Citation: International Journal of Bipolar Disorders 2016 4:4

    Content type: Guidelines

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  31. Circadian rhythm disturbances overlap with the symptoms of mood episodes and may trigger or prolong mood symptoms. There is limited research on the role of circadian disturbances in mood disorders in young peo...

    Authors: Ashlee B. Grierson, Ian B. Hickie, Sharon L. Naismith, Daniel F. Hermens, Elizabeth M. Scott and Jan Scott

    Citation: International Journal of Bipolar Disorders 2016 4:3

    Content type: Research

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  32. This review will discuss the role of childhood trauma in bipolar disorders. Relevant studies were identified via Medline (PubMed) and PsycINFO databases published up to and including July 2015. This review con...

    Authors: Monica Aas, Chantal Henry, Ole A. Andreassen, Frank Bellivier, Ingrid Melle and Bruno Etain

    Citation: International Journal of Bipolar Disorders 2016 4:2

    Content type: Review

    Published on:

  33. Lithium acts biochemically through the inositol depletion in brain cortex. At low doses, however, it is partly effective and/or ineffective, whereas in high concentrations is toxic. We would like to make one p...

    Authors: Paolo D. Pigatto, Bernardo Dell’Osso and Gianpaolo Guzzi

    Citation: International Journal of Bipolar Disorders 2016 4:1

    Content type: Letter to the Editor

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  34. As a natural phenomenon, mania without major depression will of course survive DSM-5 and ICD-11, but following its integration as a diagnosis into bipolar-I disorder (BP-I) in those manuals, BP-I will be more ...

    Authors: Jules Angst

    Citation: International Journal of Bipolar Disorders 2015 3:24

    Content type: Short communication

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  35. Lithium has been used as the gold standard in the treatment of major depressive and bipolar disorders for decades. Due to its narrow therapeutic index, lithium toxicity is a common clinical problem. Although r...

    Authors: R. Haussmann, M. Bauer, S. von Bonin, P. Grof and U. Lewitzka

    Citation: International Journal of Bipolar Disorders 2015 3:23

    Content type: Review

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  36. Bipolar disorder is often underdiagnosed and undertreated. Its detection and correct diagnosis highly relies on the report of past hypomanic or manic episodes. We investigated the recognition and awareness of ...

    Authors: Eline J. Regeer, Ralph W. Kupka, Margreet ten Have, Wilma Vollebergh and Willem A. Nolen

    Citation: International Journal of Bipolar Disorders 2015 3:22

    Content type: Research

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  37. Big data are coming to the study of bipolar disorder and all of psychiatry. Data are coming from providers and payers (including EMR, imaging, insurance claims and pharmacy data), from omics (genomic, proteomi...

    Authors: Scott Monteith, Tasha Glenn, John Geddes and Michael Bauer

    Citation: International Journal of Bipolar Disorders 2015 3:21

    Content type: Review

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  38. Some, but not all, prior investigations suggest armodafinil may have utility as an adjunctive treatment in bipolar I depression.

    Authors: Mark A Frye, Jess Amchin, Michael Bauer, Caleb Adler, Ronghua Yang and Terence A Ketter

    Citation: International Journal of Bipolar Disorders 2015 3:18

    Content type: Research

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  39. Little is known about the mood symptom experience of women with bipolar disorder during the menopausal transition (MT). Yet times of rapid hormonal decline, such as the postpartum, are associated with increase...

    Authors: Wendy K. Marsh, Bernice Gershenson and Anthony J. Rothschild

    Citation: International Journal of Bipolar Disorders 2015 3:17

    Content type: Research

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  40. The previous contribution of Duffy and colleagues suggests that a chain of behavioral events starting during childhood precedes the development of full-blown bipolar disorder. In this vein, the recent contribu...

    Authors: Ives C Passos, Karen Jansen and Flavio Kapczinski

    Citation: International Journal of Bipolar Disorders 2015 3:16

    Content type: Editorial

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  41. The management and treatment of patients with suicidal behavior is one of the most challenging tasks for health-care professionals. Patients with affective disorders are at high risk for suicidal behavior, the...

    Authors: U Lewitzka, E Severus, R Bauer, P Ritter, B Müller-Oerlinghausen and M Bauer

    Citation: International Journal of Bipolar Disorders 2015 3:15

    Content type: Review

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  42. We aimed to establish a bipolar disorder biobank to serve as a resource for clinical and biomarker studies of disease risk and treatment response. Here, we describe the aims, design, infrastructure, and resear...

    Authors: Mark A Frye, Susan L McElroy, Manuel Fuentes, Bruce Sutor, Kathryn M Schak, Christine W Galardy, Brian A Palmer, Miguel L Prieto, Simon Kung, Christopher L Sola, Euijung Ryu, Marin Veldic, Jennifer Geske, Alfredo Cuellar-Barboza, Lisa R Seymour, Nicole Mori…

    Citation: International Journal of Bipolar Disorders 2015 3:14

    Content type: Research

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  43. Reports of toxic effects on the kidney of lithium treatment emerged very soon after lithium therapy was introduced. Lithium-induced nephrogenic diabetes insipidus is usually self-limiting or not clinically dan...

    Authors: Abed N. Azab, Alla Shnaider, Yamima Osher, Dana Wang, Yuly Bersudsky and R. H. Belmaker

    Citation: International Journal of Bipolar Disorders 2015 3:13

    Content type: Review

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  44. Dietary supplements are taken by about half of Americans. Knowledge of dietary supplement use is important because they may interact with prescription drugs or other supplements, cause adverse reactions includ...

    Authors: Michael Bauer, Tasha Glenn, Jörn Conell, Natalie Rasgon, Wendy Marsh, Kemal Sagduyu, Rodrigo Munoz, Ute Lewitzka, Rita Bauer, Maximilian Pilhatsch, Scott Monteith and Peter C. Whybrow

    Citation: International Journal of Bipolar Disorders 2015 3:12

    Content type: Research

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  45. A previous factor analysis of Young Mania Rating Scale and Montgomery-Åsberg Depression Rating Scale items identified composite factors of depression, mania, sleep disturbance, judgment/impulsivity, and irrita...

    Authors: Michael J Ostacher, Trisha Suppes, Alan C Swann, James M Eudicone, Wally Landsberg, Ross A Baker and Berit X Carlson

    Citation: International Journal of Bipolar Disorders 2015 3:11

    Content type: Research

    Published on: