Skip to main content

Table 2 Validation of the M.I.N.I. module to identify individual depressive symptoms (Phase II)

From: Evaluating depressive symptoms in hypomanic and manic episodes using a structured diagnostic tool: validation of a new Mini International Neuropsychiatric Interview (M.I.N.I.) module for the DSM-5 'With Mixed Features’ specifier

Symptom Sensitivity Specificity PPV NPV κ
Depressed mood 0.87 0.73 0.79 0.82 0.60
Diminished interest/pleasure 0.87 0.63 0.69 0.84 0.50
Psychomotor retardation 0.63 0.82 0.50 0.89 0.42
Fatigue/loss of energy 0.81 0.69 0.70 0.80 0.50
Worthless/guilty feelings 0.76 0.77 0.66 0.85 0.51
Suicidal thoughts 0.90 0.90 0.72 0.97 0.74
  1. Proportions of patients experiencing each depressive symptom during a manic episode, as reported by patients using the M.I.N.I. module compared with those reported by psychiatrists using DSM-5 criteria during clinical interviewing. κ, Cohen’s kappa coefficient; NPV, negative predictive value; PPV, positive predictive value.