|
White et al. (2003)
|
42 Childhood/adolescent-onset psychosis (17.7 ± 1.7)
|
• Mean cortical thickness
|
|
24 Controls (17.7 ± 2.0)
|
• Frontal, temporal, and parietal sulci; temporal gyri
|
|
Narr et al. (2005a, b)
|
72 First episode psychosis (25.1 ± 4.7)
|
• Frontal, temporal and parietal lobes (significance set at p < 0.05, uncorrected)
|
|
78 Controls (27.3 ± 6.6)
|
• Fronto-polar, occipital lobes in patients with little or no prior antipsychotic medication
|
|
Rais et al. (2010)
|
32 Early schizophrenia, non-cannabis users (23.3 ± 5.1)
|
• Same at baseline
|
|
19 Early schizophrenia, cannabis users (21.8 ± 3.9)
|
• Five-year follow-up schizophrenia patients: right supplementary motor cortex, inferior frontal cortex, superior temporal gyrus, angular gyrus, cuneus and postcentral gyrus
|
|
31 Controls (24.7 ± 6.7)
|
|
Crespo-Facorro et al. (2011)
|
142 First episode psychosis (29.7 ± 8.7)
|
• Frontal, temporal and parietal lobes (group contrast only, not significant when covarying for gender)
|
|
83 Controls (27.6 ± 7.6)
|
|
Jung et al. (2011)
|
29 Ultra-high risk (UHR) of psychosis (22.2 ± 4.3)
|
• Mean cortical thickness: (controls = UHR) > schizophrenia
|
|
31 Schizophrenia (24.3 ± 4.2)
|
• Schizophrenia vs controls: bilateral insular, inferior frontal, STG, PCC and ACC; left superior frontal, inferior temporal and precuneus; right parahippocampal, inferior parietal, lingual and precentral cortices
|
|
29 Controls (23.2 ± 2.7)
|
|
• UHR vs controls: bilateral ACC and parahippocampal and medial frontal cortices; left STG; right lingual, inferior frontal, parietal and middle temporal cortices
|
|
• Schizophrenia vs UHR: bilateral medial frontal cortex; left STG, superior frontal, parahippocampal and inferior temporal cortices; right insula, uncus, PCC and precentral and middle temporal cortices
|
|
Lyoo et al. (2006b)
|
25 Bipolar disorder (33.8 ± 9.6)
|
• Bilateral postcentral cortex; left DLPFC, ACC, PCC, occipital cortex; right orbitofrontal, angular and fusiform cortices
|
|
21 Controls (31.5 ± 9.7)
|
• Bipolar I to bipolar II
|
|
Rimol et al. (2010, 2012)
|
173 Schizophrenia (32.3 ± 9.0)
|
• Schizophrenia vs controls: bilateral lateral and medial frontal lobe, temporal lobe, precuneus, parahippocampal and fusiform gyri, precentral gyrus, lateral and medial occipital lobe, lingual gyrus; left ACC, STG, middle temporal gyrus, inferior parietal and lingual gyrus; right medial orbitofrontal, entorhinal, supramarginal and inferior parietal cortices, isthmus of PCC
|
|
139 Bipolar disorder (35.4 ± 11.3)
|
|
207 Controls (36.2 ± 9.7)
|
|
• Bipolar vs controls, schizophrenia: no significant findings
|
|
• Bipolar I vs controls: bilateral lateral and medial frontal lobes; left orbitofrontal, posterior STG, inferior parietal gyrus; right superior frontal gyrus, supramarginal, parietal, inferior temporal and parahippocampal gyrus
|
|
• Bipolar I vs schizophrenia: no significant findings
|
|
Foland-Ross et al. (2011)
|
34 Bipolar I disorder (38.1 ± 12.0)
|
• Bilateral prefrontal cortex; left ACC and dorsomedial, ventrolateral, frontopolar cortices
|
|
31 Controls (37.8 ± 13.1)
|
• No difference between patients treated with or without lithium
|
