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Table 1 Sample characteristics of FEM patients and HCs of included studies

From: Cognitive impairment in first-episode mania: a systematic review of the evidence in the acute and remission phases of the illness

Group First author (year) Control participants FEM participants
Total Male Age (years) Education (years) Estimated IQ Total Male Age (years) Education (years) Estimated IQ score YMRS score Age of onset
N n (%) Mean (SD) Mean (SD) Score (SD) N n (%) Mean (SD) Mean (SD) Mean (SD) Mean (SD) Mean (SD)
Acute Fleck et al. (2008) 48 20 (41.6) 28.2 (7.9) 12.8 (1.4) 108.7 (9.0) 21 11 (52.4) 25.7 (9.2) 11.6 (2.2) 105.2 (10) 21.7 (11.8) NR
Lebowitz et al. (2001) 30 13 (43.3) 31.2 (8.1) 13.16 (1.1) 109.5 (8.8) 19 10 (52.6) 27.4 (7.17) 11.9 (2.0) 103.7 (8.5) 16.6 (9.1) 23.3 (6.9)
Strakowski et al. (2008) 16 9 (56) 20 (4) 13 (3) NR 16 12 (75) 19 (4) 11 (3) NR 25 (7) NR
Remission Elshahawi et al. (2011) 50 29 (58) NR NR NR 50 33 (66) 26.4 (4.7) NR NR NR NR
Hellvin et al. (2012) 110 49 (44.5) 31.1 (9.8) 13.4 (1.9) 111.6 (4.9) 34 15 (44.12) 31.2 (9.6) 13.1 (2.2) 110.9 (6.6) 2 (0 to 28)b 23 (11 to 53)b
21a 8 (38) 30.5 (10.6) 12.9 (2.3) 109.5 (5.1) 5 (0 to 19)b 17 (10 to 37)b
Lopez-Jaramillo et al. (2010) 66 44 (66.6) 37.44 (8.57) 9.61 (3.28) NR 24 16 (66.6) 37.04 (10.19) 10.92 (3.79) NR 1.21 (1.5) 25.79 (9.98)
Torres et al. (2010) 25 12 (48) 22.5 (4.8) 14.3 (2.4) 107.4 (7.7) 45 23 (51) 22.2 (3.9) 13.4 (2.4) 107.2 (7.1) 1.8 (3.7) 19.3 (4.4)
  1. YMRS, Young Mania Rating Scale; NR, not reported. aFEM participants with previously untreated manic symptoms; bmedian (min-max).