Skip to main content

Advertisement

Springer Nature is making SARS-CoV-2 and COVID-19 research free. View research | View latest news | Sign up for updates

Table 6 Rate of decrease of eGFR with age and lithium exposure (%/year)

From: Long-term lithium treatment in bipolar disorder: effects on glomerular filtration rate and other metabolic parameters

Group eGFR decrease, %/year [95% CI] (n)
Age: healthy adults Age: lithium-treated Years of lithium
All subjects 0.637 [0.497–0.777] (365) 0.710 [0.653–0.767] (312) 0.915 [0.822–1.08] (312)
Men 0.488 [0.361–0.616] (160) 0.631 [0.545–0.717] (132) 0.785 [0.546–0.717] (132)
Women 0.754 [0.580–0.928] (205) 0.756 [0.682–0.829] (180) 0.934 [0.815–1.05] (180)
  1. Lithium-treated subjects are from the present study. Data for healthy adults are adapted from Rule et al. (2004) for clearance of iothalamate. Rates of GFR decrease as %/year are computed as [initial eGFR − observed eGFR]/[initial eGFR] × 100 with 95% confidence intervals and number (n) of subjects (eGFR is in units of mL/min/1.73 m2)