Table 8 Multivariate logistic regression model for factors associated with low eGFR (<60 mL/min/1.73 m2)
Factor | Odds ratio [95% CI] | z-score | p-value |
|---|---|---|---|
Longer lithium treatment (years) | 1.07 [1.04–1.09] | 5.92 | <0.0001 |
Lower mean lithium dose (mg/day) | 1.003 [1.002–1.004] | 5.42 | <0.0001 |
Higher mean serum [Li+] | 4.47 [4.36–43.5] | 4.47 | <0.0001 |
Older age at assay | 1.04 [1.02–1.06] | 4.32 | <0.0001 |
Co-occurring medical illness | 2.11 [1.28–3.49] | 2.91 | 0.004 |