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Table 2 CRP rs1130864 genotype distribution in bipolar disorder patients with and without thyroid disorders

From: Association between CRP genetic diversity and bipolar disorder comorbid complications

 

CRP rs1130864

p value

pc

OR (CI 95%)

GG (n, %)

AG + AA (n, %)

Thyroiditis

 Yes

28 (35.9)

38 (48.7) + 12 (15.4)

0.023

0.046

1.78 (1.08–2.96)

 No

216 (49.9)

178 (41.1) + 39 (9.0)

   

Female patients

 Yes

21 (30.4)

36 (52.2) + 12 (17.4)

0.005

0.01

2.25 (1.27–4.04)

 No

112 (49.6)

94 (41.6) + 20 (8.8)

   

Early-onset BD

 Yes

11 (34.4)

16 (50.0) + 5 (15.6)

NS

NS

1.89 (0.87–4.25)

 No

104 (49.8)

89 (42.6) + 16 (7.7)

   

Rapid cycling

 Yes

22 (31.4)

34 (48.6) + 14 (20.0)

0.002

0.004

2.27 (1.33–3.95)

 No

222 (51.0)

176 (40.5) + 37 (8.5)

   
  1. CRP C-reactive protein, OR odds ratio, CI confidence interval