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Table 3 Rescue medication use during the AOM 400 maintenance phase

From: Aripiprazole once-monthly as maintenance treatment for bipolar I disorder: a 52-week, multicenter, open-label study

Medication

Enrollment source

Number of patients

Number (%) taking rescue medication

Duration (days)a

Mean

SD

Median

Lithium

De novo

379

28 (7.4)

147.9

101.8

131.5

Rollover

85

0

Total

464

28 (6.0)

147.9

101.8

131.5

Valproate

De novo

379

35 (9.2)

114.5

96.6

100

Rollover

85

1 (1.2)

84.0

84.0

Total

464

36 (7.8)

113.7

95.4

92.0

  1. Rescue medication (lithium [immediate or controlled release] or valproate [immediate or extended release]) was recommended for patients not meeting stability criteria. Only one type of rescue medication was permitted at a time. Patients meeting stability criteria were not eligible for rescue medication
  2. AOM 400 aripiprazole once-monthly 400 mg, SD standard deviation
  3. aCalculated for patients receiving AOM 400 during maintenance phase who took rescue medication during maintenance phase