Attenuated inflammatory response of monocyte-derived macrophage from patients with BD: a preliminary report

International Journal of Bipolar Disorders

Table 1 Characteristics of the sample

	Controls (n = 10)	BD-E (n = 9)	BD-L (n = 9)	F, t, x²	p value
Sex (female)^a	7 (70)	8 (88.9)	6 (66.7)	1.39	0.498
Age (years)^b	48 (14.34)	56.89 (12.23)	50.22 (14.25)	1.07	0.360
Years of education^b	14.0 (4.69)	10.00 (3.08)	13.56 (5.96)	1.99	0.158
Age of bipolar diagnosis (years)^b		43.11 (13.27)	35.56 (16.24)	1.08	0.296
Suicide attempts^a		2 (22.2)	6 (66.7)	3.60	0.058
Number of hospitalizations^b		1.44 (1.13)	3.33 (1.80)	− 2.66	0.017
BD type I^a		7 (77.8)	8 (88.9)	0.40	0.527
HAM-D^b		3.00 (1.73)	4.67 (2.12)	− 1.83	0.087
YMRS^b		1.11 (1.96)	2.44 (2.83)	− 1.16	0.263
FAST^b	5.10 (6.24)	6.33 (4.36)	45.55 (5.50)*	162.99	< 0.001
COBRA^b	6.30 (5.98)	11.78 (10.08)	24.44 (10.14)*	10.34	0.001
Marital status^a
Married	5 (50)	3 (33.3)	3 (33.3)	4.70	0.583
Work situation^a
Employed	4 (40)	3 (33.3)	2 (22.2)	20.67	0.055
Medication^a
Lithium		3 (33.3)	4 (44.4)	0.23	0.629
Anticonvulsants		6 (66.7)	6 (66.7)	0	1
Antipsychotics		7 (77.8)	8 (88.9)	0.40	0.527
Antidepressants		3 (33.3)	4 (44.4)	0.23	0.629
Benzodiazepines		3 (33.3)	1 (11.1)	1.29	0.257

Student’s t test, ANOVA (followed by Tukey) or Chi square (v2) test
Italic values indicate of p value (< 0.05)
HAM-D, Hamilton Depression Scale; YMRS, Young Mania Rating Scale; FAST, Functioning Assessment Short Test; COBRA, Cognitive Complaints in Bipolar Disorder Rating Scale
* compared to BD-E and HC
^aData expressed as %
^bData expressed as mean ± SD