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Table 4 Joint model (n = 156) with 95% confidence interval

From: Investigating the association between anxiety symptoms and mood disorder in high-risk offspring of bipolar parents: a comparison of Joint and Cox models

Sub-model Variable Estimate (95% CI) p-value
Longitudinal Age of HAM-A Measurement 0.039 (0.013, 0.065) 0.003
Female offspring 0.249 (0.008, 0.489) 0.043
Male offspring *
Lithium responder parent − 0.262 (− 0.516, − 0.007) 0.044
Lithium non-responder parent *
SES 123 0.372 (0.013, 0.731) 0.106a
SES 4 0.199 (− 0.070, 0.467)
SES 5 *
Parent onset age − 0.001 (− 0.014, 0.012) 0.914
Age at initial interview 0.023 (− 0.053, 0.007) 0.128
Cox Female offspring 0.500 (− 0.269, 1.269) 0.203
Male offspring *
Lithium responder parent 0.431 (− 0.398, 1.260) 0.308
Lithium non-responder parent *
SES 123 − 0.299 (− 1.444, 0.845) 0.274a
SES 4 0.392 (− 0.454, 1.238)
SES 5 *
Parent onset age − 0.006 (− 0.050, 0.038) 0.797
Age at initial interview − 0.115 (− 0.191, − 0.039) 0.003
Estimated trajectory of logHAMA 1.067 (0.258, 1.875) 0.010
  1. Italic values indicate significance of p-value (p < 0.05)
  2. * = Reference level
  3. ap-value obtained by a partial likelihood ratio test on 2 degrees of freedom; other p-values obtained by Wald tests