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Table 1 List of the top 20 common target genes shared by of BD GWAS dataset 1 and dataset 2

From: An integrative analysis of genome-wide association study and regulatory SNP annotation datasets identified candidate genes for bipolar disorder

Gene

SNP-associated regulatory elements

BD GWAS dataset 1

BD GWAS dataset 2

SNP

Pdataset1

SNP

Pdataset2

IPCEF1

TADs

rs9371601

1.80 × 10−6

rs9371601

4.33 × 10−9

OPRM1

TADs

rs9371601

1.80 × 10−6

rs9371601

4.33 × 10−9

SYNE1

TADs

rs9371601

1.80 × 10−6

rs9371601

4.33 × 10−9

RGS17

TADs

rs215005

6.04 × 10−6

rs214952

3.19 × 10−8

TFB1M

TADs

rs215005

6.04 × 10−6

rs214952

3.19 × 10−8

CCDC170

TADs

rs9371601

1.80 × 10−6

rs551900

3.35 × 10−8

ENSG00000235652

TADs

rs548985

6.58 × 10−6

rs551900

3.35 × 10−8

HDAC2

TADs

rs548985

6.58 × 10−6

rs551900

3.35 × 10−8

KMT2D

CIRs

rs10783301

3.32 × 10−6

rs10875914

8.27 × 10−8

ENSG00000258101

CIRs, TFBRs

rs10459221

4.20 × 10−7

rs10459232

8.81 × 10−8

RHEBL1

CIRs, TFBRs

rs7969091

3.25 × 10−7

rs7969091

8.91 × 10−8

ENSG00000257346

CIRs, lncRNAs

rs11168839

2.89 × 10−6

rs11168839

1.24 × 10−7

PRKAG1

CIRs, TFBRs

rs2304275

1.45 × 10−6

rs10875915

1.82 × 10−7

ENSG00000257913

CIRs, TFBRs

rs2293445

6.51 × 10−6

rs2293445

1.96 × 10−7

VPRBP

TADs, CIRs, TFBRs

rs2302417

4.93 × 10−9

rs736408

2.00 × 10−7

ITIH3

TADs, CIRs, TFBRs

rs4481150

1.09 × 10−8

rs736408

2.00 × 10−7

ENSG00000272822

CIRs, TFBRs

rs1054442

3.27 × 10−6

rs10783299

2.53 × 10−7

RNU6-940P

CIRs, TFBRs

rs1054442

3.27 × 10−6

rs10783299

2.53 × 10−7

WNT1

CIRs, TFBRs

rs1054442

3.27 × 10−6

rs10783299

2.53 × 10−7

LMAN2L

TFBRs

rs72809838

6.47 × 10−9

rs2271893

4.59 × 10−7

  1. TFBRs transcription factor binding regions, CIRs chromatin interactive regions, long lncRNAs non-coding RNAs regions, TADs topologically associated domains