Table 2 Comparison of treatment responses between medication groups
|  | Lithium, (n = 29)1 | Valproate, (n = 56)2 | Combination, (n = 17)3 | Statistic | p | Post-hoc analysisa | ||
|---|---|---|---|---|---|---|---|---|
1vs.2 | 1vs.3 | 2vs.3 | ||||||
Patients total (N = 102) | ||||||||
 Alda A [mean (SD)] | 6.4 (2.0) | 7.1 (1.7) | 5.5 (1.4) | F = 6.631 | 0.002 | 0.134 | 0.200 | 0.002 |
 Alda C [mean (SD)] | 2.9 (2.4) | 4.1 (2.3) | 1.5 (1.7) | F = 9.736 | < 0.001 | 0.038 | 0.133 | < 0.001 |
 Poor responder [n (%)] | 21 (72.4) | 34 (60.7) | 16 (94.1) | FE | 0.022 | 0.495 | 0.260 | 0.023 |
 CGI-BP-III-O [mean (SD)] | 2.1 (1.0) | 2.0 (0.9) | 2.9 (1.0) | F = 5.816 | 0.004 | 0.919 | 0.019 | 0.003 |
|  | Lithium, (n = 28)1 | Valproate, (n = 44)2 | Combination, (n = 15)3 | Statistic | p | Post-hoc analysisa | ||
|---|---|---|---|---|---|---|---|---|
1vs.2 | 1vs.3 | 2vs.3 | ||||||
Bipolar I disorder (N = 87) | ||||||||
 Alda A [mean (SD)] | 6.4 (2.0) | 7.2 (1.4) | 5.5 (1.9) | F = 5.822 | 0.004 | 0.139 | 0.246 | 0.004 |
 Alda C [mean (SD)] | 2.8 (2.4) | 4.1 (2.3) | 1.6 (1.8) | F = 7.799 | 0.001 | 0.047 | 0.228 | 0.001 |
 Poor responder [n (%)] | 21 (75.0) | 26 (59.1) | 14 (93.3) | FE | 0.034 | 0.310 | 0.410 | 0.033 |
 CGI-BP-III-O [mean (SD)] | 2.0 (0.7) | 1.7 (0.7) | 2.2 (0.6) | F = 3.042 | 0.053 | – | – | – |