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International Journal of Bipolar Disorders
Fig. 3 | International Journal of Bipolar Disorders

Fig. 3

From: Prefrontal dopamine D1 receptor manipulation influences anxiety behavior and induces neuroinflammation within the hippocampus

Fig. 3

IL-6-positive cells. Virus over-expression (‘ON’) is terminated (‘OFF’) following doxycycline removal. a Schematic representation of the hippocampus including the regions of interest (hippocampal CA1, CA2, CA3, CA4 and DG). b Representation of IL-6 staining in the CA3 region of the hippocampus. c Amount of IL-6-positive cells in the CA3 is significantly increased in D1R ‘OFF’ subjects compared to controls. d No significant differences in the DG were observable between groups. Means ± SEM are presented for n = 6 subject for each group. *Represent p < 0.05 Bonferroni correction indicating significant differences between relevant groups

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