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International Journal of Bipolar Disorders

Table 5 Change in suicidal rating from non-severe to severe based on MADRS Item 10

From: The effects of vagus nerve stimulation on the course and outcomes of patients with bipolar disorder in a treatment-resistant depressive episode: a 5-year prospective registry

Visit months

VNS + TAU

TAU

3

3/57 (5.3%)

3/44 (6.8%)

6

2/49 (4.1%)

4/40 (10%)

9

1/43 (2.3%)

2/32 (6.3%)

12

6/44 (13.6%)

2/28 (7.1%)

18

1/39 (2.6%)

1/22 (4.5%)

24

0/36 (0%)

0/19 (0%)

30

1/29 (3.4%)

0/14 (0%)

36

1/30 (3.3%)

0/16 (0%)

42

1/28 (3.6%)

1/15 (6.7%)

48

2/27 (7.4%)

1/18 (5.6%)

54

1/18 (5.6%)

1/10 (10%)

60

2/23 (8.7%)

0/14 (0%)

  1. The numerator denotes the number of participants who had a non-severe suicidal rating at baseline (score < 4) and developed a severe suicidal rating (score ≥ 4) at a post-baseline visit based on MADRS Item 10. The denominator denotes the number of participants who had a non-severe suicidal rating at baseline and attended a post-baseline visit
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