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Table 1 Percent observed or mean of all variables included as covariates in the models and 95% confidence intervals for the percent or mean, for full sample (n = 292) and individuals with the outcome (n = 112)

From: Predicting the risk and timing of major mood disorder in offspring of bipolar parents: exploring the utility of a neural network approach

Variable Full sample (n = 292) Individuals with outcome (n = 112)
n (%) or mean [95% CI] n (%) or mean [95% CI]
Time-fixed
 Sex (male) 121 (41.4) [35.8, 47.1] 35 (31.3) [22.6, 39.9]
 Age (at outcome or censoring) 21.0 [20.2, 21.9] 19.6 [18.6, 20.6]
 Parental lithium response 129 (44.2) [38.5, 49.9] 47 (42.0) [32.8, 51.1]
 Parental onset age 25.4 [24.4, 26.5] 25.5 [23.7, 27.4]
 Physical/sexual abuse
  Yes 30 (10.3) [6.1, 13.8] 14 (12.5) [6.3, 18.7]
  Missinga 111 (38.0) [32.4, 43.6] 32 (28.6) [20.2, 37.0]
Time-Varying
Disorders
 Subthresholdb activation 29 (9.9) [6.5, 13.4] 19 (17.0) [10.0, 23.9]
 Subthreshold depression 31 (10.6) [7.1, 14.2] 17 (15.2) [8.5, 21.6]
 Subthreshold sleep 9 (3.1) [1.1, 5.1] 2 (1.8) [0.0, 4.2]
 Subthreshold substance use 36 (12.3) [8.6, 16.1] 13 (11.6) [5.6, 17.6]
 Subthreshold anxiety 45 (15.4) [11.3, 19.6] 17 (15.2) [8.5, 21.9]
 Substance use 51 (17.5) [13.1, 21.8] 29 (25.9) [17.7, 34.0]
 Sleep 54 (18.5) [14.0, 23.0] 18 (16.1) [9.2, 22.9]
 Anxiety 87 (29.8) [24.5, 35.0] 39 (34.8) [26.0, 43.7]
 Neurodevelopmental 33 (11.3) [7.7, 14.9] 12 (10.7) [5.0, 16.5]
Number of episodes
 Major mood 0.2 [0.1, 0.3] 0.2 0.1, 0.3]
 Minor mood 0.2 [0.1, 0.3] 0.1 [0.0, 0.2]
  1. aMissing refers to having not completed the measure either due to not being age appropriate to complete or not yet completing the measure; bsee Additional file 1 for definitions of subthreshold conditions