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Table 4 Sensitivity, specificity, PPV, NPV, and AUC for the HCL-33 and HCL-33-EA in adolescents with Major Depressive Disorder and Bipolar Disorder

From: A comparison of the 33-item Hypomania Checklist with the 33-item Hypomania Checklist-external assessment for the detection of bipolar disorder in adolescents

Scales Cut-off value* Sensitivity Specificity PPV NPV AUC 95% CI
HCL-33 14 0.58 0.61 0.66 0.53 0.57 0.48–0.65
HCL-33-EA 7 0.81 0.37 0.63 0.60 0.53 0.45–0.61
  1. 95% CI 95% confidence interval for AUC, AUC area under the curve, BD  bipolar disease, HCL-33 33-item Hypomania Checklist (HCL-33), HCL-33-EA 33-item Hypomania Checklist (HCL-33) external assessment, MDD Major Depressive Disorder, NPV negative predictive value, PPV positive predictive value
  2. *The cut-off values were selected by Youden index from present study