A comparison of the 33-item Hypomania Checklist with the 33-item Hypomania Checklist-external assessment for the detection of bipolar disorder in adolescents

International Journal of Bipolar Disorders

Table 4 Sensitivity, specificity, PPV, NPV, and AUC for the HCL-33 and HCL-33-EA in adolescents with Major Depressive Disorder and Bipolar Disorder

Scales	Cut-off value^*	Sensitivity	Specificity	PPV	NPV	AUC	95% CI
HCL-33	14	0.58	0.61	0.66	0.53	0.57	0.48–0.65
HCL-33-EA	7	0.81	0.37	0.63	0.60	0.53	0.45–0.61

95% CI 95% confidence interval for AUC, AUC area under the curve, BD bipolar disease, HCL-33 33-item Hypomania Checklist (HCL-33), HCL-33-EA 33-item Hypomania Checklist (HCL-33) external assessment, MDD Major Depressive Disorder, NPV negative predictive value, PPV positive predictive value
^*The cut-off values were selected by Youden index from present study