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Table 3 Comparisons between clusters for socio-demographic and clinical characteristics

From: Associations between circadian misalignment and telomere length in BD: an actigraphy study

Variables

Aligned Morning n = 31

Misaligned n = 32

Aligned Evening n = 37

p values

Group comparisons

Sex (females)

58%

72%

57%

0.39

 

Age

54 (38–62)

44 (35–59)

38 (31–43)

0.002

AM = MisA > AE

BD type 1

77%

66%

78%

0.42

 

Age at onset

26 (20–33)

24 (20–30)

21 (19–30)

0.49

 

Duration of BD

23 (12–31)

17 (12–25)

12 (6–17)

0.0006

AM = MisA > AE

Number of episodes

8 (6–10)

10 (6–21)

8 (4–12)

0.27

 

Lithium

71%

62%

62%

0.70

 

Anticonvulsants

52%

53%

40%

0.51

 

Antipsychotics

29%

34%

32%

0.91

 

Antidepressants

32%

41%

16%

0.08

 

Benzodiazepines

19%

6%

5%

0.15

 

Body Mass Index

25 (23–28)

25 (22–26)

23 (22–28)

0.39

 

Sleep apnea risk

10%

25%

22%

0.26

 

Current tobacco use

32%

47%

65%

0.03

AM < MisA < AE

Past alcohol misuse

30%

29%

36%

0.79

 

MADRS

1 (0–3)

2 (1–6)

2 (0–4)

0.07

 
  1. Categorical variables are reported as percentage. Continuous variables are reported as median and interquartile
  2. BD: Bipolar Disorder, MADRS: Montgomery Asberg Depression Rating Scale