From: Associations between circadian misalignment and telomere length in BD: an actigraphy study
Variables | Aligned Morning n = 31 | Misaligned n = 32 | Aligned Evening n = 37 | p values | Group comparisons |
---|---|---|---|---|---|
Sex (females) | 58% | 72% | 57% | 0.39 | Â |
Age | 54 (38–62) | 44 (35–59) | 38 (31–43) | 0.002 | AM = MisA > AE |
BD type 1 | 77% | 66% | 78% | 0.42 | Â |
Age at onset | 26 (20–33) | 24 (20–30) | 21 (19–30) | 0.49 |  |
Duration of BD | 23 (12–31) | 17 (12–25) | 12 (6–17) | 0.0006 | AM = MisA > AE |
Number of episodes | 8 (6–10) | 10 (6–21) | 8 (4–12) | 0.27 |  |
Lithium | 71% | 62% | 62% | 0.70 | Â |
Anticonvulsants | 52% | 53% | 40% | 0.51 | Â |
Antipsychotics | 29% | 34% | 32% | 0.91 | Â |
Antidepressants | 32% | 41% | 16% | 0.08 | Â |
Benzodiazepines | 19% | 6% | 5% | 0.15 | Â |
Body Mass Index | 25 (23–28) | 25 (22–26) | 23 (22–28) | 0.39 |  |
Sleep apnea risk | 10% | 25% | 22% | 0.26 | Â |
Current tobacco use | 32% | 47% | 65% | 0.03 | AM < MisA < AE |
Past alcohol misuse | 30% | 29% | 36% | 0.79 | Â |
MADRS | 1 (0–3) | 2 (1–6) | 2 (0–4) | 0.07 |  |