Table 2 One-way sensitivity analysis of discounted per-patient costs
Sensitivity analysis of discounted costs for patient presenting with new episode of MDD ($*) | ||||
|---|---|---|---|---|
Original input parameters | Sensitivity analysis | No screening | Delta Study | Savings |
Prevalence of UBP in new MDD cases (16%) | Â | Â | Â | Â |
| Â | Low estimate (11%) | 49,140 | 48,622 | 518 |
| Â | High estimate (21%) | 52,731 | 50,404 | 2327 |
Sensitivity & Specificity (0.76 , 0.87) | Â | Â | Â | Â |
| Â | Low sensitivity, high specificity (0.58, 0.97) | 50,936 | 49,255 | 1681 |
| Â | High sensitivity, low specificity (0.92, 0.75) | 50,936 | 50,114 | 822 |
Cost of RBP relative to UBP (− 7604) |  |  |  |  |
|  | High estimate (150%, − 11,406) | 57,424 | 55,869 | 1554 |
|  | Low estimate (50%, − 3802) | 44,448 | 43,157 | 1291 |
Cost of MDD relative to UBP (− 1936) |  |  |  |  |
|  | High estimate (150%, − 17,904) | 74,718 | 69,732 | 4985 |
|  | Low estimated (50%, − 5968) | 27,154 | 29,293 | − 2139 |
Cost of RBP relative to MDD (+4332) | Â | Â | Â | Â |
| Â | RBP = MDD | 64,919 | 63,055 | 1864 |
Annual probability of diagnosis correction (15%) | Â | Â | Â | Â |
| Â | Low estimate (10%) | 51,402 | 49,758 | 1644 |
| Â | High estimate (20%) | 50,525 | 49,297 | 1228 |
Probability of psychiatric evaluation (75%) | Â | Â | Â | Â |
| Â | Low estimate (50%) | 50,936 | 50,728 | 207 |
| Â | High estimate (100%) | 50,936 | 48,297 | 2638 |