The association between variability, intensity, and persistence of suicidal ideation and prospective suicidal behavior in the systematic treatment enhancement program for bipolar disorder (STEP-BD) study

International Journal of Bipolar Disorders

Table 3 Odds ratios for predictors of prospective suicidal behavior (n = 1955)

	OR	95% CI	P
SI variability model
SI score dispersion × 10^a	1.21	1.05–1.40	0.01*
Age at study entry	0.98	0.96–1.00	0.02*
Gender	1.08	0.68–1.72	0.74
History of suicide attempt	2.77	1.73–4.45	< 0.01*
PDQ score	1.00	0.98–1.01	0.63
Depression severity	1.13	0.99–1.28	0.05
Depression symptom instability	1.02	0.08–13.17	0.99
Manic symptom instability	0.81	0.11–6.00	0.84
Alcohol abuse	1.52	0.83–2.79	0.17
Substance abuse	2.04	1.04–4.03	0.04*
Total number of visits	0.98	0.96–1.00	0.04*
SI intensity model
SI median score
No SI	Reference
Rare/fleeting	1.54	0.79–3.03	0.21
Several days	1.32	0.64–2.76	0.45
Nearly every day	4.81	1.99–11.60	< 0.01*
Age at study entry	0.97	0.96–0.99	0.01*
Gender	1.11	0.70–1.79	0.65
History of suicide attempt	2.79	1.73–4.50	< 0.01*
PDQ score	1.00	0.98–1.01	0.58
Depression severity	1.09	0.95–1.25	0.21
Depression symptom instability	3.34	0.25–45.28	0.37
Manic symptom instability	0.70	0.09–5.35	0.73
Alcohol abuse	1.65	0.90–3.05	0.10
Substance abuse	1.84	0.93–3.64	0.08
Total number of visits	0.98	0.96–1.00	0.03*
SI persistence model
Proportion of visits with SI × 10^a	1.10	1.00–1.22	0.05
Age at study entry	0.98	0.96–1.00	0.02*
Gender	1.09	0.70–1.73	0.70
History of suicide attempt	2.79	1.75–4.43	< 0.01*
PDQ score	0.99	0.98–1.01	0.58
Depression severity	1.11	0.98–1.25	0.10
Depression symptom instability	2.53	0.26–24.5	0.42
Manic symptom instability	0.81	0.11–5.95	0.84
Alcohol abuse	1.64	0.89–3.02	0.11
Substance abuse	1.86	0.96–360	0.07
Total number of visits	0.98	0.96–0.99	0.04*

SI suicidal ideation, PDQ Personality Disorders Questionnaire
^aA one unit change corresponds to a 10% change in variable (SI score dispersion or proportion of visits with SI); * p < .05