Table 2 Clinical and course characteristics by lifetime psychotic feature status

Clinical characteristics

 Age of onset of first mood episode [mean (s.d.)]

24.4 (9.5)

27.6 (11.5)

β = − 1.3

(− 4.3; 1.7)

0.388

23.6 (10.0)

25.0 (9.1)

β = − 1.7

(− 5.3; 1.8)

0.328

 Maximum number of symptoms during a manic or mixed episode [mean (s.d.)]

5.5 (1.2)

5.0 (1.4)

β = 0.4

(0.0; 0.9)

0.041

5.3 (1.2)

5.7 (1.4)

β = − 0.5

(− 1.0; 0.0)

0.061

 Maximum number of symptoms during a depressive episode [mean (s.d.)] ^b

7.1 (1.1)

6.9 (1.2)

β = − 0.0

(− 0.4; 0.4)

0.963

7.1 (1.1)

7.0 (1.1)

β = 0.0

(− 0.4; 0.5)

0.847

 Hallucinations or delusions

93.8

–

–

–

97.7

90.6

OR = 4.5

(0.5; 40.2)

0.180

 Any Hallucination [%]

52.1

–

–

–

67.4

39.6

OR = 3.2

(1.4; 7.7)

0.007

 Auditory Hallucinations [%]

43.8

–

–

–

58.1

32.1

OR = 2.9

(1.3; 6.8)

0.012

 Somatic Hallucinations [%]

14.6

–

–

–

23.3

7.6

OR = 3.8

(1.1; 13.1)

0.037

 Olfactory Hallucinations [%]

9.4

–

–

–

16.3

3.8

OR = 5.2

(1.0; 27.3)

0.050

 Visual Hallucinations [%]

28.1

–

–

–

41.9

17.0

OR = 3.5

(1.4; 9.0)

0.009

 Gustative Hallucinations [%]

1.0

–

–

–

2.3

0

–^c

–^c

 Any Delusion [%]

90.6

–

–

–

93.0

88.7

OR = 1.7

(0.4; 7.4)

0.473

Course characteristics

 Number of episodes

  All [median (IQR)]

5.0 (4.0)

5.0 (2.0)

β = − 0.0

(− 0.2; 0.2)^d

0.935

6.0 (5.0)

5.0 (3.0)

β = 0.2

(− 0.1; 0.4)^d

0.218

  Manic [median (IQR)]

2.0 (2.0)

1.0 (3.0)

β = 0.1

(− 0.1; 0.3)^d

0.447

2.0 (4.0)

2.0 (2.0)

β = 0.1

(− 0.2; 0.4)^d

0.339

  Mixed [median (IQR)] ^b

0.0 (1.0)

0.0 (1.0)

β = 0.0

(− 0.2; 0.3)^d

0.737

1.0 (1.0)

0.0 (1.0)

β = − 0.2

(− 0.5; 0.0)^d

 < 0.100

  Depressive [median (IQR)] ^b

2.0 (3.0)

3.0 (2.0)

β = − 0.2

(− 0.4; 0.4)^d

0.107

2.0 (3.0)

2.0 (2.0)

β = 0.1

(− 0.2; 0.4)^d

0.380

 Duration of episodes (weeks)

  All [median (IQR)]

13.9 (32.2)

13.9 (21.4)

β = − 0.0

(− 0.4; 0.4)^d

0.857

14.7 (35.6)

12.5 (26.3)

β = 0.1

(− 0.4; 0.7) ^d

0.574

  Manic [median (IQR)]

5.5 (6.5)

6.3 (6.3)

β = − 0.0

(− 0.3; 0.3)^d

0.971

5.3 (6.3)

6.0 (5.7)

β = − 0.4(− 0.7; 0.0)^d

0.073

  Mixed [median (IQR)]

10.5 (46.3)

12.5 (58.0)

β = 0.0

(− 0.8; 0.8)^d

0.979

9.0 (72.0)

12.0 (35.0)

β = 0.3

(− 0.7; 1.3)^d

0.505

  Depressive [median (IQR)] ^b

18.9 (33.5)

16.0 (22.1)

β = 0.2

(− 0.2; 0.6)^d

0.271

18.9 (33.7)

19.0 (30.3)

β = 0.1

(− 0.5; 0.7)^d

0.727

 Time spent in episodes (weeks)

  All [median (IQR)]

76.0 (135.0)

68.0 (107.0)

β = − 0.2

(− 0.4; 0.4)^d

0.905

88.0 (156.0)

60.0 (105.0)

β = 0.3

(− 0.3; 0.8) ^d

0.344

  Manic all [median (IQR)]

11.0 (19.0)

14.0 (23.0)

β = − 0.1

(− 0.5; 0.4)^d

0.801

8.5 (17.0)

13.0 (20.0)

β = − 0.3

(− 0.8; 0.2)^d

0.289

  Mixed all [median (IQR)]

24.5 (89.0)

24.0 (85.0)

β = 0.0

(− 0.9; 0.9)^d

0.993

24.5 (124.0)

24.0 (73.5)

β = 0.2

(− 0.9; 1.3)^d

0.743

  Depressive all [median (IQR)]^b

50.0 (92.0)

48.0 (70.0)

β = 0.1

(− 0.3; 0.5)^d

0.721

52.0 (103.0)

42.5 (66.0)

β = 0.3

(− 0.3; 0.8)^d

0.335

  Suicide attempts [%]

47.4

41.5

OR = 1.3

(0.7; 2.5)

0.460

62.8

34.6

OR = 3.3

(1.4; 7.8)

0.006

  Lifetime GAF [mean (s.d.)]

60.1 (11.7)

62.3 (11.5)

β = − 1.3

(− 5.0; 2.4)

0.492

55.8 (11.6)

63.6 (10.6)

β = − 7.9

(− 12.4; − 3.4)

0.001

  Current GAF [mean (s.d.)]

54.9 (15.6)

59.8 (14.5)

β = − 4.7

(− 9.6; 0.2)

0.059

50.3 (17.1)

58.6 (13.3)

β = − 8.4

(− 14.6; − 2.2)

0.009

  Worst GAF [mean (s.d.)]

28.3 (9.4)

32.4 (9.2)

β = − 3.9

(− 6.9; − 0.9)

0.011

24.2 (8.7)

31.7 (8.7)

β = − 7.5

(− 11.0; − 3.9)

 < 0.001