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Table 3 Lifetime psychiatric comorbidity by lifetime psychotic feature status

From: Psychotic features, particularly mood incongruence, as a hallmark of severity of bipolar I disorder

 

BD I all (n = 162)

BD I with psychotic features (n = 96)

Disorder

Psychotic

(n = 96)

Non-psychotic

(n = 66)

Test statistic

(95% C.I) a

p

Mood-incongruent

(n = 43)

Mood-congruent

(n = 53)

Test statistic

(95% C.I) a

P

%

%

%

%

Generalized anxiety disorder

8.4

13.9

0.5 (0.2; 1.5)

0.235

14.0

3.9

4.0 (0.8; 21.2)

 < 0.100

Agoraphobia

5.3

13.9

0.3 (0.1; 0.9)

0.032

4.7

5.8

0.8 (0.1; 5.0)

0.806

Panic disorders

9.4

6.1

1.5 (0.4; 5.5)

0.500

14.0

5.7

–b

–b

Social phobia

16.8

21.5

0.7 (0.3; 1.5)

0.357

18.6

15.4

1.3 (0.4; 3.7)

0.811

Obsessive–compulsive disorder

11.6

7.7

1.5 (0.5; 4.5)

0.518

16.3

7.7

2.3 (0.6; 8.6)

0.200

Post-traumatic stress disorder

2.1

3.1

–b

–b

4.7

0

–b

–b

Alcohol abuse

21.9

9.2

2.9 (1.1; 7.8)

0.039

25.6

18.9

1.4 (0.5; 4.0)

0.472

Alcohol dependence

17.7

27.7

0.6 (0.3; 1.2)

0.136

23.3

13.2

2.0 (0.7; 5.8)

0.230

Cannabis abuse

4.2

4.6

0.7 (0.1; 3.2)

0.601

4.7

3.8

1.3 (0.2; 9.8)

0.828

Cannabis dependence

11.5

4.6

2.2 (0.6; 8.4)

0.254

18.6

5.7

4.5 (1.1; 19.5)

0.042

Attention-deficit hyperactivity disorder

10.5

10.8

0.9 (0.8; 2.5)

0.816

16.3

5.8

3.3 (0.8; 14.2)

0.662

Childhood separation anxiety disorder

12.6

15.4

0.7 (0.3; 1.7)

0.400

16.3

9.6

1.9 (0.5; 6.4)

0.323

Childhood disruptive behavioral disorders c

14.7

6.2

2.5 (0.8; 8.2)

0.132

18.6

11.5

1.8 (0.6; 5.9)

0.317

Anti-social personality disorder

4.2

7.7

0.4 (0.1; 1.7)

0.224

4.7

3.9

1.5 (0.2; 12.1)

0.712

Anorexia nervosa

1.1

3.1

–b

–b

0

1.9

–b

–b

Bulimia nervosa

6.3

9.2

0.6 (0.2; 2.0)

0.411

7.0

5.8

–b

–b

Pathological gambling

4.2

1.5

–b

–b

7.0

1.9

–b

–b

  1. Statistically significant differences are indicated in bold. Additional variables reaching the level of p < 0.1 are in italic
  2. BD I bipolar I disorder, p p-value
  3. aModels (one model per line) adjusted for age and sex
  4. bOdd’s ratios could not be calculated due to few affected patients
  5. cIncluding oppositional defiant and conduct disorders