Fig. 1

Cumulative histograms of the proportions of previously rapid-cycling (RC; ≥ 4 recurrences in any year) or nonRC BD patients with prospectively ascertained recurrence rates (episodes/year) during follow-up assessments for ≥ 12 months. Prospective recurrence rates were < 4/year among 79.5% [69.6–87.4] of previously RC patients and 93.8% [91.9–95.3] of previously nonRC patients