Characteristics of rapid cycling in 1261 bipolar disorder patients

International Journal of Bipolar Disorders

Table 4 Multivariable logistic regression model: factors associated with rapid cycling in bipolar disorder

Factor	OR [95% CI]	χ²	p-value
More episodes/year	1.21 [1.11–1.31]	21.0	< 0.0001
Older current age	1.03 [1.01–1.05]	13.4	0.0003
More mood switching	2.81 [1.48–5.31]	10.1	0.001
BD2 > BD1	2.32 [1.33–4.02]	8.90	0.003
Lack of substance abuse	3.60 [1.25–10.4]	5.61	0.02

In addition, prospective depressions/year exceeded [hypo] manias/year with RC by 1.72-fold [1.65–1.80], and %-time depressed versus %-time-[hypo] manic by 2.47-fold [2.35–2.60]