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Table 3 Patient-related outcomes at follow-up

From: The IBER study: a feasibility randomised controlled trial of imagery based emotion regulation for the treatment of anxiety in bipolar disorder

 

Between group differencea

(TAU-IBER)

16-week follow up

Between group differencea

(TAU-IBER)

32-week follow up

Mean (95% CI) N

Effect sizeb

Mean (95% CI)

Effect sizeb

Generalised Anxiety Disorder Assessment (GAD7)

Minimal improvement: 4 points reduction (Loussaint et al. 2020)

1.4 (− 1.3 to 4.0) N = 44

0.16

0.2 (− 2.4 to 2.8) N = 44

0.02

Quick Inventory of Depressive Symptomatology–Self Report (QIDS-SR)

Minimal improvement: 28.5% reduction (Masson and Tejani 2013)

2.8 (0.5 to 5.1) N = 47

0.29

1.7 (− 1.0 to 4.4) N = 45

0.18

Altman Self-Rating Scale for Mania (ASRM)

Minimal improvement: 5.4 reduction (Altman et al. 2001)

− 0.5 (− 1.6 to 0.6) N = 48

− 0.18

− 0.5 (− 2.3 to 1.3) N = 45

− 0.18

EuroQol EQ-5D-5L, index

Minimal improvement: 0.05 increase (Payakachat et al. 2015)

− 0.07 (− 0.18 to 0.04) N = 48

− 0.11

− 0.002 (− 0.14 to 0.14) N = 48

− 0.003

EuroQol EQ-5D-5L, VAS

Minimal improvement: 5 increase (Goranitis et al. 2016)

− 3.5 (− 15.5 to 8.3) N = 48

− 0.06

− 2.0 (− 13.3 to 9.3) N = 48

− 0.03

ICEpop CAPability measure for Adults (ICECAP-A)

Minimal improvement: 0.3 increase (Goranitis et al. 2016)

−0.12 (− 0.21 to -0.03) N = 48

− 0.18

− 0.03 (− 0.13 to 0.06) N = 48

− 0.04

Oxford CAPabilities questionnaire-Mental Health (OxCAP-MH) – 117

Minimal improvement: 6.47 decease (Vergunst et al. 2017)

− 4.8 (− 8.5 to -1.1) N = 47

− 0.08

− 3.5 (− 7.4 to 0.4) N = 47

− 0.07

  1. aAdjusted for baseline value and stratification variable of trial site (Devon or Berkshire) and minimisations variables of medication status (i.e. prescribed mood stabilisers) and anxiety severity (severe anxiety being a score above 14 on the GAD7)
  2. bmean between group difference/pooled baseline SD