Table 2 Stage 2 BDM Response Profile Mixed Model Repeated Measures
Populations | Day | lurasidone (N = 5) | NRX-101 (N = 12) | NRX-101 - lurasidone (N = 17) |
|---|---|---|---|---|
LSMean | LSMean | LSDifference (p-value) | ||
No LOCF | 2 | 2.4 | 3.0 | 0.6 (0.83) |
7 | 4.6 | 1.7 | -2.9 (0.36) | |
14 | 12.9 | 2.0 | -10.9 (0.002) | |
21 | 5.7 | 5.5 | -0.2 (0.95) | |
28 | 7.7 | 4.0 | -3.7 (0.30) | |
BDM 10 Response Profile p-value | 0.042 | |||
35 | 7.3 | 3.3 | -4.0 (0.29) | |
42 | 7.7 | 4.9 | -2.8 (0.46) | |
BDM 10 Response Profile p-value | 0.09 | |||
LOCF | 2 | 2.4 | 3.0 | 0.6 (0.85) |
7 | 4.8 | 2.0 | -2.8 (0.39) | |
14 | 11.4 | 2.2 | -9.2 (0.006) | |
21 | 10.0 | 4.5 | -5.5 (0.09) | |
28 | 11.2 | 3.5 | -7.7 (0.02) | |
BDM 10 Response Profile p-value | 0.04 | |||
35 | 10.8 | 2.8 | -8.0 (0.02) | |
42 | 11.0 | 3.7 | -7.3 (0.04) | |
BDM 10 Response Profile p-value | 0.03 |