Fig. 2

Individuals with bipolar disorder show impairments in supra-second interval timing and abnormal frontal theta compared to neuronormative controls. A Schematic diagram of supra-second interval timing task. Trials begin when participants are shown a 3 s or a 12 s timing cue. Participants press the spacebar to indicate their estimation of the target interval. B Response distribution for neuronormative controls vs. individuals with bipolar disorder. C Individuals with bipolar disorder over-estimate the short interval compared to controls [left]. No differences in response distribution were detected [right]. D Individuals with bipolar disorder do not differ from controls in estimation of the long interval duration [left], however, individuals with bipolar disorder have a significantly wider response distribution compared to controls [right]. E Individuals with bipolar disorder show lower theta power compared to individuals in the neuronormative control group during the supra-second interval timing task. Mean and standard error of the mean plotted in bar graphs. Dots represent values from individual subjects. * p < 0.05