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Table 1 Reporting odds ratios (RORs) and 95% confidence intervals (95%CI) of severe weight gain for the drugs investigated (in brackets number of cases)

From: Controversies regarding lithium-associated weight gain: case–control study of real-world drug safety data

Medication (n)

ROR (95%-CI)

p-value (χ2 test)

Aripiprazole (9)

0.8 (0.3–2.1)

pval = 0.8

Carbamazepine (9)

0.9 (0.3–2.3)

pval = 0.95

Lamotrigine (8)

1

 

Risperidone (60)

1.9 (0.8–4.1)

pval = 0.2

Lithium (31)

2.1 (0.9–5.1)

pval = 0.14

Valproate (61)

2.4 (1.1–5.0)*

pval = 0.03

Quetiapine (104)

3.4 (1.3–8.4)*

pval = 0.009

Olanzapine (247)

11.5 (4.7–28.3)*

pval = 0.0005

  1. *statistically significant (p<0.05)