Lifetime risk of severe kidney disease in lithium-treated patients: a retrospective study

International Journal of Bipolar Disorders

Table 6 Results of logistic regression

Variable	Category	Reference	OR	95% CI for OR		p-value
Variable	Category	Reference	OR	Lower	Upper	p-value
Time on Li						< 0.001
	0 (1 ≤ x < 5 years)	REF
	1 (5 ≤ x < 20 years)		2.29	1.25	4.19	0.007
	2 (x ≥ 20 years)		5.85	2.54	13.44	< 0.001
Start creatinine						< 0.001
	0 (lower third)	REF
	1 (middle third)		2.15	1.27	3.64	0.004
	2 (upper third)		6.84	3.55	13.18	< 0.001

OR Odds Ratio. 95%CI 95% Confidence Interval. REF the reference category in each categorical variable. Number of patients included in the model: 515. Outcome variable: Incident CKD4 + . Predictor variable: Time on Li (categorised). Adjusted for Start Creatinine (categorised) and matching variables Sex, Matching year and Matched age group. Matching variables not presented. Predictive efficiency: 79.8% (cut-off value 0.5). Hosmer–Lemeshow test p = 0.799 (no evidence that the model is a poor fit for the data)