Articles
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Citation: International Journal of Bipolar Disorders 2019 7:9
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Metabolic profile in patients with newly diagnosed bipolar disorder and their unaffected first-degree relatives
The prevalence of metabolic syndrome and insulin resistance is twice as high in patients with bipolar disorder compared with the general population, and possibly associated with a disabling illness trajectory ...
Citation: International Journal of Bipolar Disorders 2019 7:8 -
Controversies in bipolar disorder; role of second-generation antipsychotic for maintenance therapy
In this narrative review, we discuss use of second-generation antipsychotics (SGAs) in maintenance treatment of bipolar disorder. We compare their use to historically more established treatments (particularly ...
Citation: International Journal of Bipolar Disorders 2019 7:10 -
“What if I get ill?” Perinatal concerns and preparations in primi- and multiparous women with bipolar disorder
Women with bipolar disorder have a high risk of illness relapse postpartum, including psychosis. The aim of the study was to explore how perinatal women with bipolar disorder relate to the risk. What are their...
Citation: International Journal of Bipolar Disorders 2019 7:7 -
Mortality rate trends in patients diagnosed with schizophrenia or bipolar disorder: a nationwide study with 20 years of follow-up
Patients with severe mental illness (SMI) have a reduced life expectancy of one to two decades as compared to the general population, with most years of life lost due to somatic diseases. Most previous studies...
Citation: International Journal of Bipolar Disorders 2019 7:6 -
Genetic and environmental influences on circulating NK and T cells and their relation to bipolar disorder
In previous studies we found mild deficiencies of circulating T cells in patients with bipolar disorder (BD) and children at risk for BD, correlating to a higher inflammatory state. The genetic and environment...
Citation: International Journal of Bipolar Disorders 2019 7:4 -
Differences in mood instability in patients with bipolar disorder type I and II: a smartphone-based study
Mood instability in bipolar disorder is associated with a risk of relapse. This study investigated differences in mood instability between patients with bipolar disorder type I and type II, which previously ha...
Citation: International Journal of Bipolar Disorders 2019 7:5 -
Rumination related activity in brain networks mediating attentional switching in euthymic bipolar patients
Mood disorder patients have a tendency to be more internally oriented, with difficulties in switching attentional focus, which might result in the generation of negative thoughts, such as rumination. The prese...
Citation: International Journal of Bipolar Disorders 2019 7:3 -
Show yourself, a short film to show professionals at an admission ward your ‘euthymic being’ during an admission for mania
The progress and recovery of a patient with mania during hospitalization is differently seen by professionals working at an admission ward and by relatives of the patient. Professionals often indicate that the...
Citation: International Journal of Bipolar Disorders 2019 7:2 -
Smartphone-based self-monitoring in bipolar disorder: evaluation of usability and feasibility of two systems
The aims of the present multicenter pilot study were to examine the feasibility and usability of two different smartphone-based monitoring systems (the Pulso system and the Trilogis-Monsenso system) from two I...
Citation: International Journal of Bipolar Disorders 2019 7:1 -
Lithium during pregnancy and after delivery: a review
Lithium is an effective treatment in pregnancy and postpartum for the prevention of relapse in bipolar disorder. However, lithium has also been associated with risks during pregnancy for both the mother and th...
Citation: International Journal of Bipolar Disorders 2018 6:26 -
Antidepressants in bipolar depression: an enduring controversy
The proper place and the optimal use of antidepressants in treating bipolar depression continues to be an area of great interest and greater controversy with passionate opinions more common than good studies. ...
Citation: International Journal of Bipolar Disorders 2018 6:25 -
MOGENS SCHOU: 100th anniversary of his birth
Citation: International Journal of Bipolar Disorders 2018 6:27 -
Detecting significant genotype–phenotype association rules in bipolar disorder: market research meets complex genetics
Disentangling the etiology of common, complex diseases is a major challenge in genetic research. For bipolar disorder (BD), several genome-wide association studies (GWAS) have been performed. Similar to other ...
Citation: International Journal of Bipolar Disorders 2018 6:24 -
The challenges of living with bipolar disorder: a qualitative study of the implications for health care and research
In mental health care, clinical practice is often based on the best available research evidence. However, research findings are difficult to apply to clinical practice, resulting in an implementation gap. To b...
Citation: International Journal of Bipolar Disorders 2018 6:23 -
A nationwide study on concordance with multimodal treatment guidelines in bipolar disorder
Most previous studies on concordance with treatment guidelines for bipolar disorder focused on pharmacotherapy. Few studies have included other treatment modalities.
Citation: International Journal of Bipolar Disorders 2018 6:22 -
Shared decision making in pharmacotherapy decisions, perceived by patients with bipolar disorder
Shared decision making has been promoted as standard care, but there has been debate on the possible types. On the one hand, there is a more ‘instrumental’/objective approach focused on the exchange of informa...
Citation: International Journal of Bipolar Disorders 2018 6:21 -
Clinical characteristics of patients with bipolar disorder and premorbid traumatic brain injury: a cross-sectional study
About one in ten diagnosed with bipolar disorder (BD) has experienced a premorbid traumatic brain injury (TBI), while not fulfilling the criteria of bipolar and related disorder due to another medical conditio...
Citation: International Journal of Bipolar Disorders 2018 6:19 -
Internet use by older adults with bipolar disorder: international survey results
The world population is aging and the number of older adults with bipolar disorder is increasing. Digital technologies are viewed as a framework to improve care of older adults with bipolar disorder. This anal...
Citation: International Journal of Bipolar Disorders 2018 6:20 -
Aggression among 216 patients with a first-psychotic episode of bipolar I disorder
Aggression by patients with bipolar I disorder (BD-I) is not uncommon. Identifying potential risk factors early in the illness-course should inform clinical management and reduce risk.
Citation: International Journal of Bipolar Disorders 2018 6:18 -
Thyroid and renal tumors in patients treated with long-term lithium: case series from a lithium clinic, review of the literature and international pharmacovigilance reports
Cancer had never been considered as a relevant problem in patients treated with lithium until 2015, when a document published by the European Medicine Agency concluded that long-term use of lithium might induc...
Citation: International Journal of Bipolar Disorders 2018 6:17 -
Regional cortical thinning in young adults with schizophrenia but not psychotic or non-psychotic bipolar I disorder
Schizophrenia shares some genetic risk and clinical symptoms with bipolar disorder. Clinical heterogeneity across subjects is thought to contribute to variable structural imaging findings across studies. The c...
Citation: International Journal of Bipolar Disorders 2018 6:16 -
Lack of emotional gaze preferences using eye-tracking in remitted bipolar I disorder
Bipolar disorder is associated with heightened and persistent positive emotion (Gruber in Curr Dir Psychol Sci 20:217–221, 2011; Johnson in Clin Psychol Rev 25:241–262, 2005). Yet little is known about informatio...
Citation: International Journal of Bipolar Disorders 2018 6:15 -
Aripiprazole once-monthly as maintenance treatment for bipolar I disorder: a 52-week, multicenter, open-label study
The long-acting injectable antipsychotic aripiprazole once-monthly 400 mg (AOM 400) was recently approved for maintenance treatment of bipolar I disorder (BP-I). The purpose of this study was to evaluate the s...
Citation: International Journal of Bipolar Disorders 2018 6:14 -
The perspectives of patients with lithium-induced end-stage renal disease
Lithium is the treatment of choice for patients suffering from bipolar disorder (BD) but prolonged use induces renal dysfunction in at least 20% of patient. Intensive monitoring of kidney functioning helps to ...
Citation: International Journal of Bipolar Disorders 2018 6:13 -
Behavioural biomarkers and mobile mental health: a new paradigm
Over recent decades, the field of psychiatry has allocated a vast amount of resources and efforts to make available more accurate and objective methods to diagnose, assess and monitor treatment outcomes in psy...
Citation: International Journal of Bipolar Disorders 2018 6:9 -
Regularity of self-reported daily dosage of mood stabilizers and antipsychotics in patients with bipolar disorder
Polypharmacy is often prescribed for bipolar disorder, yet medication non-adherence remains a serious problem. This study investigated the regularity in the daily dosage taken of mood stabilizers and second ge...
Citation: International Journal of Bipolar Disorders 2018 6:10 -
Monitoring of patients treated with lithium for bipolar disorder: an international survey
Adequate monitoring of patients using lithium is needed for optimal dosing and for early identification of patients with (potential) ADEs. The objective was to internationally assess how health care profession...
Citation: International Journal of Bipolar Disorders 2018 6:12 -
Add-on treatment with N-acetylcysteine for bipolar depression: a 24-week randomized double-blind parallel group placebo-controlled multicentre trial (NACOS-study protocol)
Oxidative stress and inflammation may be involved in the development and progression of mood disorders, including bipolar disorder. Currently, there is a scarcity of useful treatment options for bipolar depres...
Citation: International Journal of Bipolar Disorders 2018 6:11 -
Control charts for monitoring mood stability as a predictor of severe episodes in patients with bipolar disorder
Recurrent mood episodes and subsyndromal mood instability cause substantial disability in patients with bipolar disorder. Early identification of mood episodes enabling timely mood stabilization is an importan...
Citation: International Journal of Bipolar Disorders 2018 6:7 -
Actigraphy as an objective intra-individual marker of activity patterns in acute-phase bipolar disorder: a case series
Actigraphy could be an objective alternative to clinical ratings of motor activity in bipolar disorder (BD), which is of importance now that increased activity and energy are added as cardinal symptoms of (hyp...
Citation: International Journal of Bipolar Disorders 2018 6:8 -
Circulating antithyroid antibodies contribute to the decrease of glomerular filtration rate in lithium-treated patients: a longitudinal study
Concerns about the adverse effects of long-term treatment with lithium include reduced renal function. In the present study, we examined comorbidities which may be associated with chronic kidney disease in a c...
Citation: International Journal of Bipolar Disorders 2018 6:3 -
The association between mood state and chronobiological characteristics in bipolar I disorder: a naturalistic, variable cluster analysis-based study
Multiple types of chronobiological disturbances have been reported in bipolar disorder, including characteristics associated with general activity levels, sleep, and rhythmicity. Previous studies have focused ...
Citation: International Journal of Bipolar Disorders 2018 6:5 -
Resilience concepts in psychiatry demonstrated with bipolar disorder
The term resilience describes stress–response patterns of subjects across scientific disciplines. In ecology, advances have been made to clearly distinguish resilience definitions based on underlying mechanist...
Citation: International Journal of Bipolar Disorders 2018 6:2 -
Smartphone-based objective monitoring in bipolar disorder: status and considerations
In 2001, the WHO stated that: “The use of mobile and wireless technologies to support the achievement of health objectives (mHealth) has the potential to transform the face of health service delivery across th...
Citation: International Journal of Bipolar Disorders 2018 6:6 -
Association between CRP genetic diversity and bipolar disorder comorbid complications
Chronic low-grade inflammation is believed to contribute, at least in a subset of patients, to the development of bipolar disorder (BD). In this context, the most investigated biological marker is the acute ph...
Citation: International Journal of Bipolar Disorders 2018 6:4 -
Interrater reliability in bipolar disorder research: current practices and suggestions for enhancing best practices
Citation: International Journal of Bipolar Disorders 2018 6:1 -
Cognitive functioning following stabilisation from first episode mania
The purpose of this study was to examine cognitive functioning in people following first-episode mania relative to a demographically similar healthy control group.
Citation: International Journal of Bipolar Disorders 2017 5:39 -
Mentalization deficit in bipolar patients during an acute depressive and manic episode: association with cognitive functions
A number of studies in bipolar patients have shown a deficit in mentalization (theory of mind), one of the main aspects of social cognition. The aim of current study was to assess both cognitive and affective ...
Citation: International Journal of Bipolar Disorders 2017 5:38 -
The clinical trajectory of emerging bipolar disorder among the high-risk offspring of bipolar parents: current understanding and future considerations
Relatively little is known about the onset of bipolar disorder, yet the early illness course is already associated with significant morbidity and mortality. Therefore, characterizing the bipolar illness trajec...
Citation: International Journal of Bipolar Disorders 2017 5:37 -
Anxiety, irritability, and agitation as indicators of bipolar mania with depressive symptoms: a post hoc analysis of two clinical trials
Symptoms of anxiety, irritability, and agitation (AIA) are prevalent among patients with bipolar I disorder (BD-I) mania with depressive symptoms, and could potentially be used to aid physicians in the identif...
Citation: International Journal of Bipolar Disorders 2017 5:36 -
Animal models for bipolar disorder: from bedside to the cage
Bipolar disorder is characterized by recurrent manic and depressive episodes. Patients suffering from this disorder experience dramatic mood swings with a wide variety of typical behavioral facets, affecting o...
Citation: International Journal of Bipolar Disorders 2017 5:35 -
Does perfectionism in bipolar disorder pedigrees mediate associations between anxiety/stress and mood symptoms?
Bipolar disorder (BD) and the anxiety disorders are highly comorbid. The present study sought to examine perfectionism and goal attainment values as potential mechanisms of known associations between anxiety, ...
Citation: International Journal of Bipolar Disorders 2017 5:34 -
The relationship between self-reported borderline personality features and prospective illness course in bipolar disorder
Although bipolar disorder (BD) and borderline personality disorder (BPD) share clinical characteristics and frequently co-occur, their interrelationship is controversial. Especially, the differentiation of rap...
Citation: International Journal of Bipolar Disorders 2017 5:31 -
Erratum to: Prediction of vulnerability to bipolar disorder using multivariate neurocognitive patterns: a pilot study
In the original version of this article (Wu et al. 2017), published on 1 September 2017, the name of author ‘Bo Cao’ was wrongly displayed. In this Erratum the incorrect name and correct name are shown. The origi...
Citation: International Journal of Bipolar Disorders 2017 5:33 -
Childhood maltreatment and the medical morbidity in bipolar disorder: a case–control study
Childhood maltreatment (abuse and neglect) can have long-term deleterious consequences, including increased risk for medical and psychiatric illnesses, such as bipolar disorder in adulthood. Emerging evidence ...
Citation: International Journal of Bipolar Disorders 2017 5:30 -
Prediction of vulnerability to bipolar disorder using multivariate neurocognitive patterns: a pilot study
Bipolar disorder (BD) is a common disorder with high reoccurrence rate in general population. It is critical to have objective biomarkers to identify BD patients at an individual level. Neurocognitive signatur...
Citation: International Journal of Bipolar Disorders 2017 5:32 -
Clinical correlates of age at onset distribution in bipolar disorder: a comparison between diagnostic subgroups
Admixture analysis of age at onset (AAO) has helped delineating the clinical profile of early onset (EO) bipolar disorder (BD). However, there is scarce evidence comparing the distributional properties of AAO ...
Citation: International Journal of Bipolar Disorders 2017 5:28 -
Lifetime eating disorder comorbidity associated with delayed depressive recovery in bipolar disorder
Although eating disorders (EDs) are common in bipolar disorder (BD), little is known regarding their longitudinal consequences. We assessed prevalence, clinical correlates, and longitudinal depressive severity...
Citation: International Journal of Bipolar Disorders 2017 5:25 -
Online ethics: where will the interface of mental health and the internet lead us?
While e-health initiatives are poised to revolutionize delivery and access to mental health care, conducting clinical research online involves specific contextual and ethical considerations. Face-to-face psych...
Citation: International Journal of Bipolar Disorders 2017 5:26
- ISSN: 2194-7511 (electronic)