Articles
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Citation: International Journal of Bipolar Disorders 2023 11:15
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Structured physical exercise for bipolar depression: an open-label, proof-of concept study
Physical exercise (PE) is a recommended lifestyle intervention for different mental disorders and has shown specific positive therapeutic effects in unipolar depressive disorder. Considering the similar sympto...
Citation: International Journal of Bipolar Disorders 2023 11:14 -
Experiences that matter in bipolar disorder: a qualitative study using the capability, comfort and calm framework
When assessing the value of an intervention in bipolar disorder, researchers and clinicians often focus on metrics that quantify improvements to core diagnostic symptoms (e.g., mania). Providers often overlook...
Citation: International Journal of Bipolar Disorders 2023 11:13 -
Emotion regulation in bipolar disorder type-I: multivariate analysis of fMRI data
Bipolar disorder type-I (BD-I) patients are known to show emotion regulation abnormalities. In a previous fMRI study using an explicit emotion regulation paradigm, we compared responses from 19 BD-I patients a...
Citation: International Journal of Bipolar Disorders 2023 11:12 -
Lithium levels and lifestyle in patients with bipolar disorder: a new tool for self-management
Patients should get actively involved in the management of their illness. The aim of this study was to assess the influence of lifestyle factors, including sleep, diet, and physical activity, on lithium levels...
Citation: International Journal of Bipolar Disorders 2023 11:11 -
Reduced parenting stress following a prevention program decreases internalizing and externalizing symptoms in the offspring of parents with bipolar disorder
Offspring of parents with bipolar disorder (OBD) are at risk for developing mental disorders, and the literature suggests that parenting stress may represent an important risk factor linking parental psychopat...
Citation: International Journal of Bipolar Disorders 2023 11:10 -
Stigma in people living with bipolar disorder and their families: a systematic review
Stigma affects different life aspects in people living with bipolar disorder and their families. This study aimed to examining the experience of stigma and evaluating predictors, consequences and strategies to...
Citation: International Journal of Bipolar Disorders 2023 11:9 -
Lithium use in childhood and adolescence, peripartum, and old age: an umbrella review
Lithium is one of the most consistently effective treatment for mood disorders. However, patients may show a high level of heterogeneity in treatment response across the lifespan. In particular, the benefits o...
Citation: International Journal of Bipolar Disorders 2023 11:8 -
Risk of childhood trauma exposure and severity of bipolar disorder in Colombia
Bipolar disorder (BD) is higher in developing countries. Childhood trauma exposure is a common environmental risk factor in Colombia and might be associated with a more severe course of bipolar disorder in Low...
Citation: International Journal of Bipolar Disorders 2023 11:7 -
A systematic review on the effectiveness of dialectical behavior therapy for improving mood symptoms in bipolar disorders
Evidence-based psychotherapies available to treat patients with bipolar disorders (BD) are limited. Dialectical behavior therapy (DBT) may target several common symptoms of BD. We conducted a systematic review...
Citation: International Journal of Bipolar Disorders 2023 11:6 -
Bipolar disorder and sexuality: a preliminary qualitative pilot study
Individuals with mental health disorders have a higher risk of sexual problems impacting intimate relations and quality of life. For individuals with bipolar disorder (BD) the mood shifts might to a particular...
Citation: International Journal of Bipolar Disorders 2023 11:5 -
Long-term lithium therapy and risk of chronic kidney disease, hyperparathyroidism and hypercalcemia: a cohort study
Lithium is well recognized as the first-line maintenance treatment for bipolar disorder (BD). However, besides therapeutic benefits attributed to lithium therapy, the associated side effects including endocrin...
Citation: International Journal of Bipolar Disorders 2023 11:4 -
The association of genetic variation in CACNA1C with resting-state functional connectivity in youth bipolar disorder
CACNA1C rs1006737 A allele, identified as a genetic risk variant for bipolar disorder (BD), is associated with anomalous functional connectivity in adults with and without BD. Studies have yet to investigate the ...
Citation: International Journal of Bipolar Disorders 2023 11:3 -
Bipolar disorders in Nigeria: a mixed-methods study of patients, family caregivers, clinicians, and the community members’ perspectives
Bipolar Disorders (BDs) are chronic mental health disorders that often result in functional impairment and contribute significantly to the disability-adjusted life years (DALY). BDs are historically under-rese...
Citation: International Journal of Bipolar Disorders 2023 11:2 -
A systematic review of interventions in the early course of bipolar disorder I or II: a report of the International Society for Bipolar Disorders Taskforce on early intervention
Given the likelihood of progressive illness in bipolar disorder (BD), it is important to understand the benefits and risks of interventions administered early in illness course. We conducted a systematic revie...
Citation: International Journal of Bipolar Disorders 2023 11:1 -
Lithium induced hypercalcemia: an expert opinion and management algorithm
Lithium is the gold standard prophylactic treatment for bipolar disorder. Most clinical practice guidelines recommend regular calcium assessments as part of monitoring lithium treatment, but easy-to-implement ...
Citation: International Journal of Bipolar Disorders 2022 10:34 -
Two bipolar disorders or one? In reply to commentary by Malhi and Bell
Citation: International Journal of Bipolar Disorders 2022 10:33 -
Lunar cycling in sleep and mood in individuals with bipolar disorder
Citation: International Journal of Bipolar Disorders 2022 10:32 -
Psychotic features, particularly mood incongruence, as a hallmark of severity of bipolar I disorder
The occurrence of psychotic features within mood episodes in patients with bipolar I disorder (BD I) has been associated in some studies with a more severe clinical and socio-professional profile. In contrast,...
Citation: International Journal of Bipolar Disorders 2022 10:31 -
The bipolar two-syndrome concept: questioning the shaping of a circular argument for subtyping a dimensional disorder
Citation: International Journal of Bipolar Disorders 2022 10:30 -
The course of psychiatric symptoms in older age bipolar disorder during the COVID-19 pandemic
The COVID-19 pandemic gives us the unique opportunity to study the course of psychiatric symptoms and resilience in older adults with bipolar disorder (OABD) whilst experiencing a collective long lasting stres...
Citation: International Journal of Bipolar Disorders 2022 10:29 -
Familial load of psychiatric disorders and overall functioning in patients newly diagnosed with bipolar disorder and their unaffected first-degree relatives
Overall functioning is already impaired in patients newly diagnosed with bipolar disorder (BD) and, to a lesser degree, also in their unaffected first-degree relatives (UR). Further, aggregation of psychiatric...
Citation: International Journal of Bipolar Disorders 2022 10:28 -
Correction: New vision on the mental problems of Vincent van Gogh; results from a bottom-up approach using (semi-)structured diagnostic interviews
Citation: International Journal of Bipolar Disorders 2022 10:27 -
A physically active lifestyle is associated with lower long-term incidence of bipolar disorder in a population-based, large-scale study
Physical activity has been proposed to be beneficial for the symptomatic control of bipolar disorder, but the duration of the effects, sex-specific mechanisms, and impact of exercise intensity are not known.
Citation: International Journal of Bipolar Disorders 2022 10:26 -
The interplay of daily affect and impulsivity measured by mobile surveys in bipolar disorder
Impulsivity is a prominent feature of bipolar disorder associated with various negative sequelae; moreover, it may be a precursor to shifts in affect or mood, but little is known about its association with aff...
Citation: International Journal of Bipolar Disorders 2022 10:25 -
Efficacy and safety of adjunctive therapy to lamotrigine, lithium, or valproate monotherapy in bipolar depression: a systematic review and meta-analysis of randomized controlled trials
The efficacy and safety of adjunctive therapy are unclear in bipolar depression. In this systematic review and meta-analysis, we aimed to evaluate the efficacy and safety of second-generation antipsychotic, la...
Citation: International Journal of Bipolar Disorders 2022 10:24 -
Clinical research diagnostic criteria for bipolar illness (CRDC-BP): rationale and validity
In the 1970 s, scientific research on psychiatric nosology was summarized in Research Diagnostic Criteria (RDC), based solely on empirical data, an important source for the third revision of the official nomen...
Citation: International Journal of Bipolar Disorders 2022 10:23 -
The effect of mindfulness-based cognitive therapy on rumination and a task-based measure of intrusive thoughts in patients with bipolar disorder
Preliminary evidence suggests that Mindfulness-Based Cognitive Therapy (MBCT) is a promising treatment for bipolar disorder (BD). A proposed working mechanism of MBCT in attenuating depressive symptoms is redu...
Citation: International Journal of Bipolar Disorders 2022 10:22 -
Differences between bipolar disorder types 1 and 2 support the DSM two-syndrome concept
To compare characteristics of bipolar disorder patients diagnosed as DSM-5 types I (BD-1) vs. II (BD-2).
Citation: International Journal of Bipolar Disorders 2022 10:21 -
A randomised, double-blind, placebo-controlled study to evaluate the safety and efficacy of lamotrigine in the maintenance treatment of Chinese adult patients with bipolar I disorder
Lamotrigine is approved as a maintenance therapy for bipolar I disorder in many countries, including China in 2021. This study evaluated the efficacy and safety of lamotrigine in controlling relapse and/or rec...
Citation: International Journal of Bipolar Disorders 2022 10:20 -
Long-term work disability due to type I and II bipolar disorder: findings of a six-year prospective study
Bipolar disorder (BD) is one of the leading causes of disability worldwide. However, the prevalence and predictors of long-term work disability among patients with type I and II BD have scarcely been studied. ...
Citation: International Journal of Bipolar Disorders 2022 10:19 -
Psychedelics in the treatment of unipolar and bipolar depression
This is a narrative review about the role of classic and two atypical psychedelics in the treatment of unipolar and bipolar depression. Since the 1990s, psychedelics experience a renaissance in biomedical rese...
Citation: International Journal of Bipolar Disorders 2022 10:18 -
The association between variability, intensity, and persistence of suicidal ideation and prospective suicidal behavior in the systematic treatment enhancement program for bipolar disorder (STEP-BD) study
This study sought to examine the association between prospective suicidal behavior and variability, intensity, and persistence of suicidal ideation (SI) in bipolar disorder (BD).
Citation: International Journal of Bipolar Disorders 2022 10:17 -
Euthymic patients with predominantly manic polarity avoid happy faces in a dot probe task
Some studies suggest a mood-congruent attentional bias in bipolar patients. However, for euthymic patients, especially in dependence on the predominant polarity, there is little and inconsistent data. A cleare...
Citation: International Journal of Bipolar Disorders 2022 10:16 -
Using decision-analysis modelling to estimate the economic impact of the identification of unrecognised bipolar disorder in primary care: the untapped potential of screening
Patients with bipolar disorder are often unrecognised and misdiagnosed with major depressive disorder leading to higher direct costs and pressure on the medical system. Novel screening tools may mitigate the p...
Citation: International Journal of Bipolar Disorders 2022 10:15 -
Associations between circadian misalignment and telomere length in BD: an actigraphy study
Life expectancy is significantly decreased in bipolar disorder (BD). This is associated with accelerated cellular aging which can be estimated by telomere length (TL). However, specific determinants of shorter...
Citation: International Journal of Bipolar Disorders 2022 10:14 -
Is cognitive behaviour therapy applicable to individuals diagnosed with bipolar depression or suboptimal mood stabilizer treatment: a secondary analysis of a large pragmatic effectiveness trial
Efficacy trials of medications and/or psychological interventions for bipolar disorders (BD) aim to recruit homogenous samples of patients who are euthymic and such populations show high levels of adherence to...
Citation: International Journal of Bipolar Disorders 2022 10:13 -
Anticipating manic and depressive transitions in patients with bipolar disorder using early warning signals
In bipolar disorder treatment, accurate episode prediction is paramount but remains difficult. A novel idiographic approach to prediction is to monitor generic early warning signals (EWS), which may manifest i...
Citation: International Journal of Bipolar Disorders 2022 10:12 -
Environmental factors in offspring of parents with mood disorders and their role in parent–child transmission: findings from a 14-year prospective high-risk study
The factors involved in the transmission of mood disorders are only partially elucidated. Aside from genes, the family environment might play a crucial role in parent–child transmission. Our goals were to (1) ...
Citation: International Journal of Bipolar Disorders 2022 10:11 -
Evaluating the quality, safety, and functionality of commonly used smartphone apps for bipolar disorder mood and sleep self-management
Individuals with bipolar disorder (BD) are increasingly turning to smartphone applications (apps) for health information and self-management support. While reviews have raised concerns regarding the effectiven...
Citation: International Journal of Bipolar Disorders 2022 10:10 -
Omega-3 fatty acids in bipolar patients with a low omega-3 index and reduced heart rate variability: the “BIPO-3” trial
Research suggests that a low omega-3 index may contribute to the low heart rate variability and the increased risk of cardiovascular morbidity and mortality in bipolar disorders. However, so far, no interventi...
Citation: International Journal of Bipolar Disorders 2022 10:9 -
The relations between executive functions and occupational functioning in individuals with bipolar disorder: a scoping review
Patients with bipolar disorder experience impairments in their occupational functioning, despite remission of symptoms. Previous research has shown that neurocognitive deficits, especially deficits in executiv...
Citation: International Journal of Bipolar Disorders 2022 10:8 -
A pilot trial of quetiapine, lithium, or placebo added to divalproex sodium for hypomanic or manic episodes in ambulatory adults with bipolar I disorder
Many patients with bipolar I disorder do not respond to monotherapy treatment with mood-stabilizing medications, and combination regimens are commonly used in both inpatient and outpatient settings for the acu...
Citation: International Journal of Bipolar Disorders 2022 10:7 -
Sleep disturbances in the context of neurohormonal dysregulation in patients with bipolar disorder
Sleep dysfunction is a core symptom in bipolar disorder (BD), especially during major mood episodes. This study investigated the possible link between subjective and objective sleep disturbances in inter-episo...
Citation: International Journal of Bipolar Disorders 2022 10:6 -
A call for improving lithium literacy among clinicians and patients
Citation: International Journal of Bipolar Disorders 2022 10:5 -
Estimated glomerular filtration rate in Korean patients exposed to long-term lithium maintenance therapy
Lithium-induced nephrotoxicity has long been debated. However, it has been rarely explored in Asian populations. The aim of the present study was to assess the effect of lithium maintenance therapy on estimate...
Citation: International Journal of Bipolar Disorders 2022 10:4 -
Dissecting the genetic architecture of suicide attempt and repeated attempts in Korean patients with bipolar disorder using polygenic risk scores
Bipolar disorder (BD) has the greatest suicide risk among mental and physical disorders. A recent genome-wide association study (GWAS) of European ancestry (EUR) samples revealed that the genetic etiology of s...
Citation: International Journal of Bipolar Disorders 2022 10:3 -
Neuropsychological exponents for the driving ability in remitted bipolar patients
Bipolar disorder (BD) is associated with cognitive deficits regardless of the phase of the disease. Medications used in treatment are an additional factor that may affect cognitive performance. Poor cognitive ...
Citation: International Journal of Bipolar Disorders 2022 10:2 -
The big five model in bipolar disorder: a latent profile analysis and its impact on longterm illness severity
Using a personality typing approach, we investigated the relationship between personality profiles and the prediction of longterm illness severity in patients with bipolar disorder (BD). While previous researc...
Citation: International Journal of Bipolar Disorders 2022 10:1 -
A comparison of the 33-item Hypomania Checklist with the 33-item Hypomania Checklist-external assessment for the detection of bipolar disorder in adolescents
Adolescents with bipolar disorder (BD) are often misdiagnosed as having major depressive disorder (MDD), which delays appropriate treatment and leads to adverse outcomes. The aim of this study was to compare t...
Citation: International Journal of Bipolar Disorders 2021 9:41
- ISSN: 2194-7511 (electronic)