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  1. Research

    Long-term use of lurasidone in patients with bipolar disorder: safety and effectiveness over 2 years of treatment

    Bipolar disorder is a chronic illness with a 2-year recurrence rate of approximately 50% among individuals receiving treatment in the community. The aim of this 18-month, open-label, continuation study was to ...

    Andrei Pikalov, Joyce Tsai, Yongcai Mao, Robert Silva, Josephine Cucchiaro and Antony Loebel

    International Journal of Bipolar Disorders 2017 5:9

    Published on: 2 March 2017

  2. Research

    A pilot study to determine whether combinations of objectively measured activity parameters can be used to differentiate between mixed states, mania, and bipolar depression

    Until recently, actigraphy studies in bipolar disorders focused on sleep rather than daytime activity in mania or depression, and have failed to analyse mixed episodes separately. Furthermore, even those studi...

    Jan Scott, Arne E. Vaaler, Ole Bernt Fasmer, Gunnar Morken and Karoline Krane-Gartiser

    International Journal of Bipolar Disorders 2017 5:5

    Published on: 1 March 2017

  3. Research

    Pilot study of a culturally adapted psychoeducation (CaPE) intervention for bipolar disorder in Pakistan

    Despite the use of maintenance medication, recurrence rates in bipolar affective disorder (BPAD) are high. To date, there are no clinical trials that have investigated the use of psychological interventions i...

    Muhammad Ishrat Husain, Imran B. Chaudhry, Raza R. Rahman, Munir M. Hamirani, Nasir Mehmood, Peter M. Haddad, John Hodsoll, Allan H. Young, Farooq Naeem and Nusrat Husain

    International Journal of Bipolar Disorders 2017 5:3

    Published on: 11 February 2017

  4. Review

    A systematic review of the frequency and severity of manic symptoms reported in studies that compare phenomenology across children, adolescents and adults with bipolar disorders

    In the last two decades, there has been a significant increase in the diagnosis of Bipolar Disorder (BD) in children. The notion of prepubertal onsets of BD is not without controversy, with researchers debatin...

    Faye Ryles, Thomas D. Meyer, Jaime Adan-Manes, Iain MacMillan and Jan Scott

    International Journal of Bipolar Disorders 2017 5:4

    Published on: 3 February 2017

  5. Research

    American tertiary clinic-referred bipolar II disorder versus bipolar I disorder associated with hastened depressive recurrence

    Bipolar disorder (BD) is a chronic, frequently comorbid condition characterized by high rates of mood episode recurrence and suicidality. Little is known about prospective longitudinal characterization of BD ...

    Bernardo Dell’Osso, Saloni Shah, Dennis Do, Laura D. Yuen, Farnaz Hooshmand, Po W. Wang, Shefali Miller and Terence A. Ketter

    International Journal of Bipolar Disorders 2017 5:2

    Published on: 25 January 2017

  6. Short communication

    The seroprevalence of antithyroid peroxidase antibodies in bipolar families and bipolar twins: results from two longitudinal studies

    Previous studies of our group among bipolar offspring and bipolar twins showed significant higher prevalence’s and levels of antithyroid peroxidase antibodies (TPO-Abs) in offspring and co-twins (without a moo...

    G. Snijders, L. de Witte, E. Mesman, S. Kemner, R. Vonk, R. Brouwer, W. A. Nolen, H. A. Drexhage and M. H. J. Hillegers

    International Journal of Bipolar Disorders 2017 5:1

    Published on: 20 January 2017

  7. Research

    Serum concentrations of mood stabilizers are associated with memory, but not other cognitive domains in psychosis spectrum disorders; explorative analyses in a naturalistic setting

    Mood stabilizers like lithium and anticonvulsants are used in bipolar and related psychotic disorders. There is a lack of knowledge of the relationship of these medications and cognition in the psychosis spect...

    Nils Eiel Steen, Monica Aas, Carmen Simonsen, Ingrid Dieset, Martin Tesli, Mari Nerhus, Erlend Gardsjord, Ragni Mørch, Ingrid Agartz, Ingrid Melle, Anja Vaskinn, Olav Spigset and Ole A. Andreassen

    International Journal of Bipolar Disorders 2016 4:24

    Published on: 9 December 2016

  8. Review

    Aims and structure of the German Research Consortium BipoLife for the study of bipolar disorder

    Bipolar disorder is a severe and heterogeneous mental disorder. Despite great advances in neuroscience over the past decades, the precise causative mechanisms at the transmitter, cellular or network level have...

    Philipp S. Ritter, Felix Bermpohl, Oliver Gruber, Martin Hautzinger, Andreas Jansen, Georg Juckel, Tilo Kircher, Martin Lambert, Christoph Mulert, Andrea Pfennig, Andreas Reif, Otto Rienhoff, Thomas G. Schulze, Emanuel Severus, Thomas Stamm and Michael Bauer

    International Journal of Bipolar Disorders 2016 4:26

    Published on: 21 November 2016

  9. Short communication

    Bipolar disorder in the digital age: new tools for the same illness

    “Nothing is more difficult than to ascertain the length of time that a maniacal patient can exist without sleep.”—Dr. Sutherland (Br J Psychiatry 7(37):1–19, 1861). Dr. Sutherland’s patient was suffering from an ...

    John Torous, Paul Summergrad and S. Nassir Ghaemi

    International Journal of Bipolar Disorders 2016 4:25

    Published on: 17 November 2016

  10. Reseach

    Bipolar disorder in children and adolescents: diagnostic inpatient rates from 2000 to 2013 in Germany

    Despite growing consensus on nosology and epidemiology of bipolar disorder (BD) in minors, differences remain. We contribute to this discussion by measuring long-term trends in the inpatient discharge rates of...

    Pradeep Rao, Julie K. Moore, Richard Stewart, Kevin Runions, Natasha Bear, Janice W. Y. Wong, Martin Holtmann and Florian D. Zepf

    International Journal of Bipolar Disorders 2016 4:23

    Published on: 11 November 2016

  11. Research

    Psychometric properties and validation of a four-item version of the Strauss–Carpenter scale in bipolar disorder

    Bipolar disorder is a chronic illness that impairs functioning and affects the quality of life of patients. The onset of this illness usually occurs at an early age, and the risk of relapse remains high for de...

    Susana Alberich, Sara Barbeito, Itxaso González-Ortega, Amaia Ugarte, Patricia Vega, Sonia Ruiz de Azúa, Purificación López, Iñaki Zorrilla and Ana González-Pinto

    International Journal of Bipolar Disorders 2016 4:22

    Published on: 18 October 2016

  12. Research

    No differences in visual theory of mind abilities between euthymic bipolar patients and healthy controls

    Research on theory of mind (ToM) abilities in patients with bipolar disorder has yielded conflicting results. Meta-analyses point to a stable moderate impairment in remitted patients, but factors such as subsy...

    Silvia Haag, Paula Haffner, Esther Quinlivan, Martin Brüne and Thomas Stamm

    International Journal of Bipolar Disorders 2016 4:20

    Published on: 12 October 2016

  13. Research

    Symptom profiles and illness course among Anabaptist and Non-Anabaptist adults with major mood disorders

    Anabaptists comprise large and growing Amish and Mennonite populations with a unique genetic heritage and cultural background. Little is known about the symptoms and course of major mood disorders in Anabaptis...

    Kelly E. Gill, Stephanie A. Cardenas, Layla Kassem, Thomas G. Schulze and Francis J. McMahon

    International Journal of Bipolar Disorders 2016 4:21

    Published on: 12 October 2016

  14. Case report

    Mixed mania associated with cessation of breastfeeding

    This case chronicles the unique presentation of psychotic mixed mania in a female 5 months after parturition and 1 week following breastfeeding discontinuation, highlighting a rarely recognized mania risk fact...

    Kristen A. Schmidt, Brian A. Palmer and Mark A. Frye

    International Journal of Bipolar Disorders 2016 4:18

    Published on: 5 September 2016

  15. Research

    Online information seeking by patients with bipolar disorder: results from an international multisite survey

    Information seeking is an important coping mechanism for dealing with chronic illness. Despite a growing number of mental health websites, there is little understanding of how patients with bipolar disorder us...

    Jörn Conell, Rita Bauer, Tasha Glenn, Martin Alda, Raffaella Ardau, Bernhard T. Baune, Michael Berk, Yuly Bersudsky, Amy Bilderbeck, Alberto Bocchetta, Letizia Bossini, Angela Marianne Paredes Castro, Eric Yat Wo Cheung, Caterina Chillotti, Sabine Choppin, Maria Del Zompo…

    International Journal of Bipolar Disorders 2016 4:17

    Published on: 24 August 2016

    The Erratum to this article has been published in International Journal of Bipolar Disorders 2017 5:18

  16. Research

    Behavioral measures and self-report of impulsivity in bipolar disorder: no association between Stroop test and Barratt Impulsiveness Scale

    Impulsivity as a tendency to act quickly without considering future consequences has been proposed as a dimensional factor in bipolar disorder. It can be measured using behavioral tasks and self-report questio...

    Elisa Sophie Strasser, Paula Haffner, Jana Fiebig, Esther Quinlivan, Mazda Adli and Thomas Josef Stamm

    International Journal of Bipolar Disorders 2016 4:16

    Published on: 17 August 2016

  17. Research

    Current irritability associated with hastened depressive recurrence and delayed depressive recovery in bipolar disorder

    Current irritability is associated with greater retrospective and current bipolar disorder (BD) illness severity; less is known about prospective longitudinal implications of current irritability. We examined ...

    Laura D. Yuen, Saloni Shah, Dennis Do, Shefali Miller, Po W. Wang, Farnaz Hooshmand and Terence A. Ketter

    International Journal of Bipolar Disorders 2016 4:15

    Published on: 30 July 2016

  18. Research

    Does CRP predict outcome in bipolar disorder in regular outpatient care?

    The association between inflammation and the course of mood disorders is receiving increased attention. This study aims to investigate whether a sub-group of patients with BD can be identified for which a high...

    Sonya M. Balukova, Bartholomeus C. M. Haarman, Rixt F. Riemersma-van der Lek and Robert A. Schoevers

    International Journal of Bipolar Disorders 2016 4:14

    Published on: 18 July 2016

  19. Research

    Toxoplasma gondii exposure may modulate the influence of TLR2 genetic variation on bipolar disorder: a gene–environment interaction study

    Genetic vulnerability to environmental stressors is yet to be clarified in bipolar disorder (BD), a complex multisystem disorder in which immune dysfunction and infectious insults seem to play a major role in ...

    José Oliveira, Rémi Kazma, Edith Le Floch, Meriem Bennabi, Nora Hamdani, Djaouida Bengoufa, Mehdi Dahoun, Céline Manier, Frank Bellivier, Rajagopal Krishnamoorthy, Jean-François Deleuze, Robert Yolken, Marion Leboyer and Ryad Tamouza

    International Journal of Bipolar Disorders 2016 4:11

    Published on: 20 May 2016

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